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Now showing items 111-120 of 122
Brain tumours at the Kenyatta National Hospital, Nairobi
(University of Nairobi, 2000)
Conceptual basis of 'early' and 'delayed' reinfection with Plasmodium falciparum.
(University of Nairobi, 2000)
A total of 96 residents in Kenya, who had life-long, intense exposure to malaria, donated blood samples for malaria parasite smears [date not given]. Each volunteer was then treated with a single dose of 3 tablets of ...
Effect of improved stoves on prevalence of acute respiration infection and conjunctivitis among children and women in a rural community in kenya
(2000-01)
Objectives: To estimate the effect of improved stoves on the prevalence of ARI and conjunctivitis among children aged below five years and women aged between 15 and 60 years.
Method: A field trial or intervention study ...
Novel thymidylate synthase enhancer region alleles in African populations
(2000-12)
Thymidylate synthase (TS) regulates the production of DNA synthesis precursors and is an important target of cancer chemotherapy. A polymorphic tandem repeat sequence in the enhancer region of the TS promoter was previously ...
Acute hepatic failure in India: a perspective from the East
(2000)
Acute hepatic failure (AHF) in India almost always presents with encephalopathy within 4 weeks of the onset of acute hepatitis. Further subclassification of AHF into hyperacute, acute and subacute forms may not be necessary ...
Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes
(University of Nairobi., 2000-04)
AIMS:
Albendazole (ABZ; methyl 5-propylthio-1H-benzimidazol-2-yl carbamate) is a broad spectrum anthelmintic whose activity resides both in the parent compound and its sulphoxide metabolite (ABS). There are numerous ...
Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection.
(, 2000-05)
Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T cell recognition, may, in part, account for the observed differences in human immunodeficiency virus type 1 (HIV-1) susceptibility. To ...
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
(, 2000)
Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ...
Persistently HIV-1 seronegative Nairobi sex workers are susceptible to in vitro infection
(2000)
OBJECTIVE:
To evaluate whether resistance to HIV-1 infection in a subset of highly exposed sex workers correlates with resistance at the cellular level.
DESIGN:
In vitro evaluation of susceptibility to infection by ...
Autopsy study of HIV-1-positive and HIV-1-negative adult medical patients in Nairobi, Kenya
(2000)
HIV infection has now been consistently identified as the major cause of death in young Africans in both urban and rural areas. In Africa, several studies have defined the clinical presentation of HIV disease but there ...