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Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?
(University of Nairobi, 2021-06)
Background: Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook ...
Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?
(University of Nairobi, 2021)
Background
Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook ...
Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?
(University of Nairobi, 2021-06)
Background: Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook ...
Latent tuberculosis among household contacts of pulmonary tuberculosis cases in Nairobi, Kenya
(University of Nairobi, 2020)
Introduction: Household Contacts (HHCs) of Pulmonary Tuberculosis (PTB) patients have a higher risk of latent tuberculosis infection (LTBI). However, its prevalence and risk factors among adults living with PTB patients ...
Serological Evidence of Exposure to Onyong-nyong and Chikungunya Viruses in Febrile Patients of Rural Taita-taveta County and Urban Kibera Informal Settlement in Nairobi, Kenya
(University of Nairobi, 2022-06)
Several alphaviruses, such as chikungunya (CHIKV) and Onyong-nyong (ONNV), are endemic in Kenya and often cause outbreaks in different parts of the country. We assessed the seroprevalence of alphaviruses in patients with ...
Epidemiological and clinical characteristics of patients hospitalised with COVID-19 in Kenya: a multicentre cohort study
(University of Nairobi, 2022-05)
Objectives: To assess outcomes of patients admitted to hospital with COVID-19 and to determine the predictors of mortality.
Setting: This study was conducted in six facilities, which included both government and privately ...
An Empiric Tool to Identify Kenyans Living With Hiv Who Will Have Unsuppressed Viremia 18 Months Following Treatment Initiation to Guide Differentiated Care Models
(University of Nairobi, 2022)
Background: With the global push towards universal access to Antiretroviral Treatment (ART), patient numbers are increasing, further straining already under-resourced healthcare systems in sub-Saharan Africa. A simple ...
Rethinking the syndemic of tuberculosis and dysglycaemia: a Kenyan perspective on dysglycaemia as a neglected risk factor for tuberculosis
(University of Nairobi, 2023)
Background: The END TB 2035 goal has a long way to go in low-income and low/middle-income countries (LICs and LMICs) from the perspective of a non-communicable disease (NCD) control interaction with tuberculosis (TB). The ...
Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults
(University of Nairobi, 2023)
BackgroundSARS-CoV-2 infection in Africa has been characterized by a less severe disease profile than what has been observed elsewhere, but the profile of SARS-CoV-2-specific adaptive immunity in these mainly asymptomatic ...
Age and CD4+ T cell counts are inversely associated with HIV drug resistance mutations in treatment naive female sex workers
(University of Nairobi, 2023)
The increasing prevalence of human immunodeficiency virus (HIV) drug resistance mutations (HIVDRM) in untreated seropositive persons has consequences for future treatment options. This is extremely important in key populations ...