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Now showing items 31-40 of 44
CCR5, RANTES, and SDF-1 polymorphisms and mother-to-child HIV-1 transmission
(2010)
Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, ...
Building capacity in implementation science research training at the University of Nairobi
(University of Nairobi, 2016)
Background
Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential ...
Interprofessional fellowship training for emerging global health leaders in Africa to improve HIV prevention and care: the afya bora consortium
(University of Nairobi, 2016)
HIV continues to challenge health systems, especially in low- and middle-income countries in Sub-Saharan Africa. A qualified workforce of transformational leaders is required to strengthen health systems and introduce ...
Breast Milk HIV-1 RNA Levels and Female Sex Are Associated With HIV-1–Specific CD8+ T-Cell Responses in HIV-1–Exposed, Uninfected Infants in Kenya
(2011)
Background. Although evidence supports a relationship between human immunodeficiency virus (HIV)–1 exposure and HIV-1−specific CD8+ T cell responses, studies have not demonstrated a direct association between the quantity ...
High Rates of Exclusive Breastfeeding in Both Arms of a Peer Counseling Study Promoting EBF Among HIV-Infected Kenyan Women
(2016)
Background: Exclusive breastfeeding (EBF) is recommended for 6 months after delivery as the optimal infant feeding method and is especially important for prevention of mother-to-child HIV transmission (PMTCT). However, EBF ...
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya:
(2010)
Background: Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It is
important to define correlates of mortality in order to improve outcome.
Methods: HIV-1-infected ...
Cofactors for HIV-1 Incidence during Pregnancy and Postpartum Period
(2010)
Objectives
To estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.
Design
Retrospective study among women who were HIV seronegative during pregnancy.
Methods
Mothers ...
Longitudinal Assessment of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon Responses during the First Year of Life in HIV-1-Infected Infants
(2005)
Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in viral control has not been ...
Determinants of Per-Coital-Act HIV-1 Infectivity Among African HIV-1–Serodiscordant Couples
(2012)
Background. Knowledge of factors that affect per-act infectivity of human immunodeficiency virus type 1 (HIV-1) is important for designing HIV-1 prevention interventions and for the mathematical modeling of the spread of ...
Human Immunodeficiency Virus Is Associated With Higher Levels of Systemic Inflammation Among Kenyan Adults Despite Viral Suppression
(University of Nairobi, 2020)
Background: Systemic inflammation independently predicts future cardiovascular events and is associated with a 2-fold increase in cardiovascular disease (CVD) risk among persons living with human immunodeficiency virus ...