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Now showing items 181-190 of 278
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
(2010)
Most persons who are infected with human immunodeficiency virus type 1 (HIV-1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated and is associated with increased plasma and genital ...
Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk.
(Univesity of Nairobi, 2010-09)
BACKGROUND:
The risk of sexual transmission of HIV-1 is strongly associated with the level of HIV-1 RNA in plasma making reduction in HIV-1 plasma levels an important target for HIV-1 prevention interventions. A ...
Angioarchitecture of brain arteriovenous malformations and the risk of bleeding: an analysis of patients in northeastern malaysia.
(University of Nairobi, 2010-01)
BACKGROUND:
Central nervous system arteriovenous malformation (AVM) is a vascular malformation of the brain and involves entanglement of veins and arteries without an intervening capillary bed. Affecting predominantly ...
Genetic characterization of HIV type 1 among patients with suspected immune reconstitution inflammatory syndrome after initiation of antiretroviral therapy in Kenya.
(2010)
Antiretroviral therapy (ART) has improved the survival of HIV patients but is also associated with unique manifestations of disease in some subjects during the initial months of therapy. Immune reconstitution inflammatory ...
Cancrum oris in an adult with human immunodeficiency virus infection: case report.
(2010)
New cases of cancrum oris in adults are rare and there are no previous reports in the literature from Kenya. Since noma is related to factors associated with poverty and immunosuppression, reducing the incidence of noma ...
Non-susceptibility genes to Bombyx densovirus type 1, Nid-1 and nsd-1, affect distinct steps of the viral infection pathway
(2010)
In the silkworm Bombyx mori, densovirus type 1 (BmDNV-1) replicates only in the midgut and causes fatal disease. Resistance to BmDNV-1 is determined by two genes, nsd-1 and Nid-1, respectively. Neither of them has been ...
Variations in the anatomy of ansa cervicalis
(University of Nairobi, 2010-08)
With the emerging utilisation of ansa cervicalis in nerve reconstructive surgery, it is important for surgeons to be conversant with the anatomy of these nerves. This descriptive cross sectional study aimed at describing ...
Comparative Tolerability And Efficacy Of Stavudine 30 Mg Versus Stavudine 40 Mg In Patients On Combination Antiretroviral Therapy In Kenya
(University of Nairobi, 2010-02-05)
Stavudine- containing regimens are currently the most widely used first-line anti-HIV treatment option in Kenya. This study compared the efficacy and tolerability of stavudine at two dose levels in patients attending a HIV ...
A Safe Motherhood project in Kenya: assessment of antenatal attendance, service provision and implications for PMTCT.
(2010)
OBJECTIVES:
To investigate uptake and provision of antenatal care (ANC) services in the Uzazi Bora project: a demonstration-intervention project for Safe Motherhood and prevention of mother-to-child transmission of HIV ...
Reduced Hiv-1 Long Terminal Repeat Transcription In Subjects With Protective Interferon Regulatory Factor-1 Genotype: A Potential Mechanism Mediating Resistance To Infection By Hiv-1.
(University of Nairobi, 2010-05)
We previously described the polymorphism in the interferon regulatory factor-1 (IRF-1) gene as a novel correlate of resistance to HIV-1 infection in a Kenyan female sex worker cohort. However, the underlying mechanisms ...