Search
Now showing items 171-180 of 361
HIV-1 Clade D Is Associated with Increased Rates of CD4 Decline in a Kenyan Cohort
(University of Nairobi, 2012)
HIV-1 is grouped phylogenetically into clades, which may impact rates of HIV-1 disease progression. Clade D infection in particular has been shown to be more pathogenic. Here we confirm in a Nairobi-based prospective female ...
A cascade of biochemical and physiological markers in pathological disorders
(2012)
A few years ago, a neurophysiology lecturer in the Department of Medical Physiology, University of
Nairobi, was doing some research on possible indicators in malnourished children. The first indicator he
chose was the ...
Characteristic Radiological and Histological Patterns of Fibrous Dysplasia and Ossifying Fibroma of the Jaws at University of Nairobi Dental Teaching Hospital
(2012)
Objective: To characterize the diagnostic features of ossifying fibroma (OF) and fibrous dysplasia (FD) of the jaw bones. Study Design: A histopathological and radiological analysis with full clinical documentation. Setting: ...
Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR).
(2012)
Thienopyridine-derivatives (ticlopidine, clopidogrel, and prasugrel) are the primary antiplatelet agents. Thrombotic thrombocytopenic purpura (TTP) is a rare drug-associated syndrome, with the thienopyridines being the ...
Gadolinium-induced nephrogenic systemic fibrosis: the rise and fall of an iatrogenic disease.
(2012)
In 2006, nephrologists in Denmark unexpectedly identified chronic kidney disease (CKD) patients with a new syndrome, nephrogenic systemic fibrosis (NSF). Subsequently, 1603 NSF patients were reported to the Food and Drug ...
A survey of psychosis risk symptoms in Kenya
(2012)
Defining the prepsychotic state in an effort to prevent illness progression and the development of disorders such as schizophrenia is a rapidly growing area of psychiatry. The presentation of psychotic symptoms can be ...
The role of G protein gene GNB3 C825T Polymorphism in HIV-1 acquisition, progression and immune activation
(2012)
Background
The GNB3 C825T polymorphism is associated with increased G protein-mediated signal transduction, SDF-1α-mediated lymphocyte chemotaxis, accelerated HIV-1 progression, and altered responses to antiretroviral ...
Analgesic and anti-inflammatory activities of 9-Hexacosene and Stigmasterol isolated from Mondia whytei
(University of Nairobi, 2012)
The aim of the study was to ascertain the analgesic properties of Mondia whytei
roots and to isolate and characterize the active constituents. Bioactivity guided
fractionation of the chloroform root extract yielded ...
Antimicrobial activity of various extracts of the sea urchin Tripneustes gratilla (Echinoidea)
(University of Nairobi, 2012)
Background:
Marine invertebrates rely solely on innate immune
mechanisms, the cellular component of which is
characterized by hemocytes that phagocytize microbe
s and secrete soluble antimicrobial and cytotoxic substances. ...
In-Depth Analysis of Patient-Clinician Cell Phone Communication during the WelTel Kenya1 Antiretroviral Adherence Trial
(2012)
Background
The WelTel Kenya1 trial demonstrated that text message support improved adherence to antiretroviral therapy (ART) and suppression of HIV-1 RNA load. The intervention involved sending weekly messages to patients ...