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Genital inflammation predicts HIV-1 shedding independent of plasma viral load and systemic inflammation
(2012)
In women, genital HIV-1 RNA levels predict the risk of
HIV-1 transmission independent of plasma viral load. To better
understand the factors that contribute to genital HIV-1 shedding, we
evaluated the relationships ...
The impact of HIV-1 infection and exposure on natural killer (NK) cell phenotype in Kenyan infants during the first year of life
(2012)
Natural killer (NK) cells play an important role in the containment of HIV replication during primary infection, though their functions are impaired during chronic HIV infection. Infants experience more rapid HIV disease ...
Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding
(2007)
Antiretroviral therapy (ART) may decrease HIV-1 infectivity in women by reducing genital HIV-1 shedding. To evaluate the time course and magnitude of decay in cervical and vaginal HIV-1 shedding as women initiate ART. This ...