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Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?
(2005)
Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...
Coma scales for children with severe falciparum malaria
(1997-03)
The Blantyre coma scale (BCS) is used to assess children with severe falciparum malaria, particularly as a criterion for cerebral malaria, but it has not been formally validated. We compared the BCS to the Adelaide coma ...
Effectiveness of chloroquine and sulfadoxine/pyrimethamine combination in the treatment of falciparum malaria in a malaria endemic area of Kenya
(1998)
A study on the comparative efficacy of two antimalarial drugs, namely chloroquine and sulfadoxine/pyrimethamine combination in the treatment of falciparum malaria was carried out in Siaya District, Nyanza Province of Kenya. ...