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Predicting pregnancy in HIV-1-discordant couples.
(University of Nairobi, 2010-10)
This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy ...
Distance from home to study clinic and risk of follow-up interruption in a cohort of HIV-1-discordant couples in Nairobi, Kenya.
(University of Nairobi, 2012)
BACKGROUND:
Longitudinal studies of HIV-1-infected individuals or those at risk of infection are subject to missed study visits that may have negative consequences on the care of participants and can jeopardize study ...
Reply to “Male Involvement' in Women and Children's HIV Prevention: Challenges in Definition and Interpretation”
(University of Nairobi, 2011)
Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition
(University of Nairobi., 2010-06)
The C868T single nucleotide polymorphism (SNP) in the CD4 receptor encodes an amino acid change that could alter its structure and influence human immunodeficiency virus (HIV-1) infection risk. HIV-1-infected pregnant women ...
Seroprevalence of measles IgG among HIV-1-infected and uninfected Kenyan adults.
(University of Nairobi, 2014-02)
Despite global efforts to reduce measles incidence, outbreaks continue to occur in developing countries where HIV-1-infected adults represent a vulnerable population. Immunization campaigns have targeted children, although ...
Incident HSV-2 Infections Are Common Among HIV-1-discordant Couples.
(University of Nairobi, 2013)
Background. The synergy between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus type 1 (HIV-1) is well known, but lack of knowledge about the epidemiology of HSV-2 acquisition in HIV-1-discordant couples ...
Illness during pregnancy and bacterial vaginosis are associated with in-utero HIV-1 transmission
(University of Nairobi., 2010-01)
HIV-1 transmission in utero accounts for 20-30% of vertical transmission events in breast-feeding populations. In a prospective study of 463 HIV-1-infected mothers and infants, illness during pregnancy was associated with ...
Dual contraceptive method use in HIV-serodiscordant Kenyan couples.
(University of Nairobi, 2016)
BACKGROUND:
World Health Organization (WHO) guidelines recommend dual contraceptive method use with condoms and another contraceptive to reduce both incidence of HIV/sexually transmitted infection transmission and ...
Higher transplacental pathogen-specific antibody transfer among pregnant women randomized to triple antiretroviral treatment versus short course zidovudine.
(University of Nairobi, 2017)
BACKGROUND:
HIV-1 infection may impair transplacental antibody transfer to infants. The impact of highly active antiretroviral treatment (ART) given during pregnancy on transplacental antibody transport is unknown.
M ...