Search
Now showing items 1-10 of 19
Cellular Immune Responses And Susceptibility To HIV-1 Superinfection: A Case-control Study.
(University of Nairobi, 2012-03)
A case-control study was performed to determine the effects of HIV-1-specific cellular immune responses on the odds of acquiring a second HIV-1 infection (superinfection). Changes in the frequency of cytokine-producing or ...
Association of HIV infection with distribution and viral load of HPV types in Kenya: a survey with 820 female sex workers
(2010)
BACKGROUND:
Human papillomavirus (HPV) and HIV are each responsible for a considerable burden of disease. Interactions between these infections pose substantial public health challenges, especially where HIV prevalence ...
Establishing and sustaining a healthy vaginal environment: analysis of data from a randomized trial of periodic presumptive treatment for vaginal infections
(2011)
Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by Gram ...
Loss to Follow-Up as a Competing Risk in an Observational Study of HIV-1 Incidence
(2013)
OBJECTIVE:
Conventional survival estimates may be biased if loss to follow-up (LTF) is associated with the outcome of interest. Our goal was to assess whether the association between sexual risk behavior and HIV-1 ...
Prospective study of correlates of vaginal Lactobacillus colonisation among high-risk HIV-1 seronegative women
(2011)
OBJECTIVE:
Vaginal colonisation with Lactobacillus species is characteristic of normal vaginal ecology. The absence of vaginal lactobacilli, particularly hydrogen peroxide (H(2)O(2))-producing isolates, has been associated ...
Hiv-1 Superinfection Is Associated With An Accelerated Viral Load Increase But Has A Limited Impact On Disease Progression.
(University of Nairobi, 2014)
OBJECTIVE
HIV-1 superinfection occurs frequently in high-risk populations, but its clinical consequences remain poorly characterized. We undertook this study to determine the impact of HIV-1 superinfection on disease ...
Perceived stigma among patients receiving antiretroviral treatment: a prospective randomised trial comparing an m-DOT strategy with standard-of-care in Kenya.
(2010)
HIV and AIDS remain highly stigmatised. Modified directly observed therapy (m-DOT) supports antiretroviral treatment (ART) adherence but little is known about its association with perceived stigma in resource-constrained ...
The prevalence of human papillomavirus infection in Mombasa, Kenya.
(2011)
OBJECTIVES:
A human papillomavirus (HPV) prevalence survey was done in Mombasa, Kenya, to improve the knowledge of HPV prevalence and genotype distribution in sub-Saharan African countries overall, and in women of ...
Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women.
(University of Nairobi, 2020)
A reservoir of HIV-infected cells that persists despite suppressive antiretroviral therapy (ART) is the source of viral rebound upon ART cessation and the major barrier to a cure. Understanding reservoir seeding dynamics ...
Systemic Cytokine Levels Show Limited Correlation with Risk of HIV-1 Acquisition.
(University of Nairobi, 2014-01)
It has been hypothesized that immune activation and inflammation may increase HIV-1 susceptibility and that cytokines may be useful biomarkers for risk. Within a prospective cohort, we conducted a nested case-control ...