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Evaluation of performance of the Gen-Probe human immunodeficiency virus type 1 viral load assay using primary subtype A, C, and D isolates from Kenya.
(University of Nairobi, 2000-07)
Accurate and sensitive quantification of human immunodeficiency virus type 1 (HIV-1) RNA has been invaluable as a marker for disease prognosis and for clinical monitoring of HIV-1 disease. The first generation of commercially ...
Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial
(2004)
To test the hypothesis that micronutrient supplementation decreases genital HIV-1 shedding, a double-blind, randomized, placebo-controlled trial of 6 weeks of multivitamin plus selenium supplementation vs. placebo was ...
Virus load during primary Human Immunodeficiency Virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women.
(2002)
We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes ...
Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle
(University of Nairobi, 1998-10)
Cervical and vaginal secretions from 17 women infected with human immunodeficiency virus type 1 (HIV-1) were evaluated daily through the course of one menstrual cycle for HIV-1 DNA (21-31 visits per woman). HIV-1-infected ...
Hormonal contraception, vitamin A deficiency, and other risk factors for shedding of HIV-1 infected cells from the cervix and vagina.
(University of Nairobi, 1997-09)
BACKGROUND: Factors that influence shedding of HIV-1 infected cells in cervical and vaginal secretions may be important determinants of sexual and vertical transmission of the virus. We investigated whether hormonal ...
Breast-milk infectivity in human immunodeficiency virus type 1-infected mothers.
(University of Nairobi., 2003-03)
Human immunodeficiency virus type 1 (HIV-1) is transmitted through blood, genital secretions, and breast milk. The probability of heterosexual transmission of HIV-1 per sex act is.0003-.0015, but little is known regarding ...
Selenium deficiency is associated with shedding of HIV-1--infected cells in the female genital tract.
(2001)
Objective: To assess the relation between selenium deficiency and vaginal or cervical shedding of HIV-1-infected cells.
Design: Cross-sectional study of 318 HIV-1 seropositive women in Mombasa, Kenya.
Methods: Vaginal ...
Vitamin A supplementation and human immunodeficiency virus type 1 shedding in women: results of a randomized clinical trial.
(2002)
Observational studies have associated vitamin A deficiency with vaginal shedding of human immunodeficiency virus (HIV) type 1-infected cells and mother-to-child HIV-1 transmission. To assess the effect of vitamin A ...
Injectable contraceptive use and genital ulcer disease during the early phase of HIV-1 infection increase plasma virus load in women.
(2004)
We examined the association between host factors present near the time of human immunodeficiency virus type 1 (HIV-1) acquisition and subsequent virus loads, in a prospective cohort study of women in Mombasa, Kenya. Women ...