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Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya.
(University of Nairobi, 2008-07)
Humoral immunity, and specifically immunoglobulin A (IgA) that is directed against human immunodeficiency virus (HIV)-1, may contribute to protection against HIV-1 acquisition at mucosal surfaces. HIV-1-specific IgA has ...
Morbidity And Mortality In Breastfed And Formula-fed Infants Of Hiv-1-infected Women: A Randomized Clinical Trial
(University of Nairobi, 2002-11-21)
CONTEXT: Breastfeeding among women infected with human immunodeficiency virus type 1 (HIV-1) is associated with substantial risk of HIV-1 transmission, but little is known about the morbidity risks associated with formula ...
Effect of breastfeeding on mortality among HIV-1 infected women: a randomised trial.
(2001)
We have completed a randomised clinical trial of breastfeeding and formula feeding to identify the frequency of breastmilk transmission of HIV-1 to infants. However, we also analysed data from this trial to examine the ...
Association of Levels of HIV-1–Infected Breast Milk Cells and Risk of Mother-to-Child Transmission
(2004)
Understanding how the level of human immunodeficiency virus type 1 (HIV-1)–infected breast milk cells (BMCs) affects HIV transmission via breast-feeding can shed light on the mechanism of infection and aid in establishing ...
Strategies to improve HIV test acceptance and uptake of interventions in PMCT sites
(2004)
HIV testing in the antenatal clinic is an entry point for interventions to prevent mother to child transmission. It is therefore crucial that all women learn their HIV status during pregnancy. The approach used may influence ...
CCR5 Promoter Polymorphisms in a Kenyan Perinatal Human Immunodeficiency Virus Type 1 Cohort: Association with Increased 2-Year Maternal Mortality
(2001)
The CCR5 chemokine receptor acts as a coreceptor with CD4 to permit infection by primary macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains. The CCR5Δ32 mutation, which is associated with resistance to ...
Contextualising the paediatric HIV epidemic: a review
(University of Nairobi., 2006-12)
OBJECTIVE:
To draw attention to the sub-optimal care that HIV-infected children are receiving in Africa.
DATA SOURCES:
Relevant published literature.
DATA SYNTHESIS:
Sub-optimal response to paediatric HIV infection ...
Short-term effect of zidovudine on plasma and genital human immunodeficiency virus type 1 and viral turnover in these compartments
(University of Nairobi., 2003-07)
The effect of zidovudine on plasma and genital human immunodeficiency virus type 1 (HIV-1) was determined in 42 antiretroviral-naive HIV-1-seropositive women in Nairobi. After 7 days of zidovudine treatment, HIV-1 RNA ...
Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya
(University of Nairobi., 2008-07)
Humoral immunity, and specifically immunoglobulin A (IgA) that is directed against human immunodeficiency virus (HIV)-1, may contribute to protection against HIV-1 acquisition at mucosal surfaces. HIV-1-specific IgA has ...
Breast-milk infectivity in human immunodeficiency virus type 1-infected mothers.
(University of Nairobi., 2003-03)
Human immunodeficiency virus type 1 (HIV-1) is transmitted through blood, genital secretions, and breast milk. The probability of heterosexual transmission of HIV-1 per sex act is.0003-.0015, but little is known regarding ...