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Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression.
(University of Nairobi, 2009-10)
The determinants of a broad neutralizing antibody (NAb) response and its effect on human immunodeficiency virus type 1 (HIV-1) disease progression are not well defined, partly because most prior studies of a broad NAb ...
HIV-1 evolution in gag and env is highly correlated but exhibits different relationships with viral load and the immune response
(2009)
OBJECTIVE:
To evaluate relationships between HIV-1 evolution, including immune evasion, and markers of disease progression during chronic infection.
DESIGN:
HIV-1 evolution and disease progression markers were evaluated ...