Search
Now showing items 1-6 of 6
The Breadth and Potency of Passively Acquired Human Immunodeficiency Virus Type 1-Specific Neutralizing Antibodies Do Not Correlate with the Risk of Infant Infection[down-pointing small open triangle]
(2011)
Although a major goal of human immunodeficiency virus type 1 (HIV-1) vaccine efforts is to elicit broad and
potent neutralizing antibodies (NAbs), there are no data that directly demonstrate a role for such NAbs in
protection ...
Effects of Valcyclovir on markers of disease Progression in Postpartum Women Co-Infected with HIV-1 andHerpes Simplex Virus-2
(2012-06)
Objective:
Herpes simplex virus type 2 (HSV-2) suppression has been shown to reduce HIV-1 disease progression in nonpregnant
women and men, but effects on pregnant and postpartum women have not been described.
Methods:
We ...
Evaluation of a single round polymerase chain reaction assay using dried blood spots for diagnosis of HIV-1 infection in infants in an African setting
(2011)
Background
The aim of this study was to develop an economical 'in-house' single round polymerase chain reaction (PCR) assay using filter paper-dried blood spots (FP-DBS) for early infant HIV-1 diagnosis and to evaluate ...
HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads
(2012)
There are limited data describing the functional characteristics of HIV-1 specific antibodies in breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to bind HIV-1 envelope, neutralize ...
Incidence and Correlates of HIV-1 RNA Detection in the Breast Milk of Women Receiving HAART for the Prevention of HIV-1 Transmission
(2012)
Background
The incidence and correlates of breast milk HIV-1 RNA detection were determined in intensively sampled women receiving highly active antiretroviral therapy (HAART) for the prevention of mother-to-child HIV-1 ...
Breast Milk HIV-1 RNA Levels and Female Sex Are Associated With HIV-1–Specific CD8+ T-Cell Responses in HIV-1–Exposed, Uninfected Infants in Kenya
(2011)
Background. Although evidence supports a relationship between human immunodeficiency virus (HIV)–1 exposure and HIV-1−specific CD8+ T cell responses, studies have not demonstrated a direct association between the quantity ...