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Outcome of the first medicines utilization research in Africa group meeting to promote sustainable and rational medicine use in Africa.
(University of Nairobi, 2015)
The second Medicines Utilization Research in Africa (MURIA) group workshop and symposium again brought researchers together from across Africa to improve their knowledge of drug utilization (DU) methodologies and exchange ...
How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial.
(University of Nairobi, 2015-10)
OBJECTIVE:
This study's objective is to analyze training methods clinicians reported as most and least helpful during the DSM-5 Cultural Formulation Interview field trial, reasons why, and associations between demographic ...
Knowledge, Attitude and Practices of health care workers on corticosteroid adverse drug events in rheumatologic, respiratory and dermatologic clinics in a teaching hospital in Nairobi
(University of Nairobi, 2015-06)
Background:
Corticosteroids form the
cornerstone of management for a myriad
of rheumatological, dermatological
and chronic respiratory tract diseases.
Whereas these drugs are crucial in
reducing morbidity and ...
Gender differences in treatment outcomes among 15-49 year olds with smear-positive pulmonary tuberculosis in Kenya
(University of Nairobi, 2015)
OBJECTIVE:
To determine gender differences in treatment outcomes among 15-49 year olds with smear-positive pulmonary tuberculosis (PTB) and factors associated with poor outcomes in Kenya.
DESIGN:
Retrospective ...
Host Genetic and Viral Determinants of HIV-1 RNA Set Point among HIV-1 Seroconverters from Sub-Saharan Africa
(University of Nairobi, 2015-09-03)
ABSTRACT
We quantified the collective impact of source partner HIV-1 RNA levels, human leukocyte antigen (HLA) alleles, and innate re-
sponses through Toll-like receptor (TLR) alleles on the HIV-1 set point. Data came ...
Molecular signatures of immune activation and epithelial barrier remodeling are enhanced during the luteal phase of the menstrual cycle: implications for HIV susceptibility
(University of Nairobi, 2015)
Variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in non-human primate models and ex vivo human ...
Enabling the development and deployment of next generation point-of-care diagnostics
(University of Nairobi, 2015-05-14)
Safety and efficacy of antenatal iron supplementation in a malaria-endemic area in Kenya: A randomised trial
(University of Nairobi, 2015)
Objectives: Whereas coverage of antenatal iron supplementation is low and benefits are uncertain, there are concerns that it can increase the burden of malaria, with potentially devastating effects on maternal and neonatal ...
Virus-encoded microRNA contributes to the molecular profile of EBV-positive burkitt lymphomas.
(University of Nairobi, 2015-07)
Burkitt lymphoma (BL) is an aggressive neoplasm characterized by consistent morphology and phenotype, typical clinical behavior and distinctive molecular profile. The latter is mostly driven by the MYC over-expression ...
Genomic epidemiology of the current wave of artemisinin resistant malaria
(University of Nairobi, 2015)
Artemisinin resistant Plasmodium falciparum is advancing across Southeast Asia in a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which ...