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Correlates of age at attainment of developmental milestones in HIV-infected infants receiving early antiretroviral therapy
(University of Nairobi, 2015)
Background: Infant HIV-1 infection is associated with impaired neurologic and motor development. Antiretroviral therapy (ART) has the potential to improve developmental outcomes but the relative contributions of pre-ART ...
Sustained responses to measles revaccination in HIV Infected Children on ART in Kenya
(University of Nairobi, 2015-02-26)
Background: Despite recent advances in reducing measles incidence in Africa, a number of measles outbreaks have occurred in countries with high HIV prevalence. One
hypothesis is that there is a growing population of ...
T cell anergy and activation are associated with suboptimal humoral responses to measles revaccination in HIV-infected children on antiretroviral therapy in Nairobi, Kenya
(University of Nairobi, 2015)
HIV-infected children are less capable of mounting and maintaining protective humoral responses to vaccination against measles compared to HIV-uninfected children. This poses a public health challenge in countries with ...
High mortality in HIV-infected children diagnosed in hospital underscores need for faster diagnostic turnaround time in prevention of mother-to-child transmission of HIV (PMTCT) programs
(University of Nairobi, 2015)
Background
Despite expanded programs for prevention of mother-to-child HIV transmission (PMTCT), HIV-infected infants may not be diagnosed until they are ill. Comparing HIV prevalence and outcomes in infants diagnosed ...