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What impact would an HIV/AIDS vaccine have on the HIV/AIDS epidemic in Kenya?

Anzala, Omu; Mutua, Gaudensia Nzembi; Oyugi, Fredrick Jack Odia; Mohamed, Bashir Farah; Achia, Thomas; Stover, John (2012-09)

Objective: To estimate the potential impact of an HIV/AIDS Vaccine in Kenya. Design: The Kenyan HIV/AIDS epidemic was modeled using the most current data from national sources including epidemiology and behavioral surveillance. ...

Psychiatric morbidity among HIV-infected children and adolescents in a resource-poor Kenyan urban community

Kamau, Judy W.; Kuria, Wangari; Mathai, Muthoni; Atwoli, Lukoye; Kangethe, Rachael (2012)

The course of HIV / AIDS in children has been transformed from an acute to a chronic one with the advent of Anti-Retroviral Therapy. The aim of this study was to determine the prevalence and pattern of psychiatric morbidity ...

Patient satisfaction with integrated HIV and antenatal care services in rural Kenya.

Vo, BN; Cohen, CR; Smith, RM; Bukusi, EA; Onono, MA; Schwartz, K; Washington, S; Turan, JM (2012)

A cluster randomized controlled trial was initiated in Kenya to determine if full integration (FI) of HIV care, including HAART, into antenatal care (ANC) clinics improves health outcomes among HIV-infected women and exposed ...

Barriers to Antiretroviral Initiation in HIV-1-Discordant Couples

Guthrie, Brandon L; Choi, Robert Y; Liu, Amy Y; Mackelprang, Romel D; Rositch, Anne F; Bosire, Rose; Manyara, Lucy; Gatuguta, Anne; Kiarie, James N; Farquhar, Carey (2011)

BACKGROUND In Kenya and much of sub-Saharan Africa, nearly half of all couples affected by HIV are discordant. Antiretroviral therapy (ART) slows disease progression in HIV-1-infected individuals, and reduces transmission ...

Prevalence and characteristics of articular manifestations in Human Immunodeficiency Virus Infection

Ekwom, PE; Oyoo, GO; Amayo, EO; Muriiithi, IM (2010)

Background: Articular manifestations have been reported in HIV infection with a prevalence ranging from 2.5 to 68%. Objectives: To determine the prevalence, types and characteristics of articular manifestations in the ...

Increased risk of HIV acquisition among Kenyan men with human papillomavirus infection

Smith, Jennifer S; Moses, Stephen; Hudgens, Michael; Parker, Corette B; Agot, Kawango; Maclean, Ian; Ndinya-Achola JO.; Snijders, Peter J F; Meijer, Chris J L M; Bailey, Robert C (2010-06-01)

Background Few data are available concerning the effect of human papillomavirus (HPV) infection on HIV acquisition. Methods HIV-seronegative, sexually active 18-24 year-old Kenyan men within a randomized trial ...

Prevalence of specific neutralizing antibodies against Sendai virus in populations from different geographic areas Implications for AIDS vaccine development using Sendai virus vectors

Hara, Hiroto; Hironaka, Takashi; Inoue, Makoto; Iida, Akihiro; Shu, Tsugumine; Hasegawa, Mamoru; Nagai, Yoshiyuki; Falsey, Ann R.; Kamali, Anatoli; Anzala, Omu; Sanders, Eduard J.; Karita, Etienne; Vasan, Sandhya; Lombardo, Angela; Parks, Christopher L.; Sayeed, Eddy; Krebs, Marietta; Cormier, Emmanuel; Ackland, James; Price, Matthew A.; Excler, Jean-Louis (2011-06)

A Sendai Virus (Sev) vector is being developed for an HIV immunogen. SeV is not known to cause disease in humans. Because it is genetically and antigenically related to human parainfluenza virus type 1 (hPIV-1), it is ...

Utility of Quantitative Sensory Testing and Screening Tools in Identifying HIV-Associated Peripheral Neuropathy in Western Kenya: Pilot Testing

Cettomai, Deanna; Kwasa, Judith; Kendi, Caroline; Birbeck, Gretchen L.; Price, Richard W.; Bukusi, EA; Cohen, Craig R.; Meyer, Ana-Claire (2010)

Background/Aim: Neuropathy is the most common neurologic complication of HIV but is widely under-diagnosed in resource-constrained settings. We aimed to identify tools that accurately distinguish individuals with moderate/severe ...

Feasibility and Safety of Cervical Biopsy Sampling for Mucosal Immune Studies in Female Sex Workers from Nairobi, Kenya

Hasselrot, Klara; Cheruiyot, Juliana; Kimani, Joshua; Ball, Terry B; Kaul, Rupert; Hirbod, Taha (2012)

Background There is an urgent need to improve our understanding of the mucosal immuno-pathogenesis of HIV acquisition in the female genital tract, particularly in high-risk women such as female sex workers (FSWs). ...

Building capacity for cervical cancer screening in outpatient HIV clinics in the Nyanza province of western Kenya

Huchko, Megan J; Bukusi, EA; Cohen, Craig R (2011)

Objective To evaluate outcomes of cervical cancer screening within HIV care and treatment clinics in Kenya. Methods Beginning in October 2007, visual inspection with acetic acid (VIA), colposcopy, and loop electrosurgical ...