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Now showing items 171-180 of 182
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model
(ASC, 2017-02-23)
Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds with improved in vivo ...
The Pattern of Orbital Fractures Managed at Two Referral Centers in Nairobi, Kenya.
(Wolters Kluwer, 2017)
Orbital fractures are one of the commonest injuries in mid-face trauma and can lead to significant functional and cosmetic defects. This study was aimed at analyzing the pattern of orbital fractures at 2 referral centers ...
Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study.
(BMC, 2017-11-20)
Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of ...
Dental age estimation in a group of Kenyan children using Willems' method: a radiographic study.
(Taylor and Francis, 2017-11-07)
BACKGROUND:
Radiographic study of developing teeth provides a reliable indication of chronological age. In Kenya, dentists are often required to estimate age. However, there is a paucity of publications on the performance ...
Differences in acute retroviral syndrome by HIV-1 subtype in a multicentre cohort study in Africa.
(BMC, 2017-11)
Symptoms of acute retroviral syndrome (ARS) may be used to identify patients with acute HIV-1 infection who seek care. ARS symptoms in African adults differ by region. We assessed whether reporting of ARS was associated ...
Prevalence of fibromyalgia syndrome in diabetics with chronic pain at the Kenyatta National Hospital
(University of Nairobi, 2017)
Background: Fibromyalgia Syndrome (FMS), an increasingly recognized disorder with heightened response to pressure, characterized by Chronic Widespread Pain (CWP), for which no other cause can be identified. Diabetes Mellitus ...
Antioxidant and anti-inflammatory activities of selected medicinal plants from western Kenya
(KeSoBAP, 2017-12)
Background: Globally, the increase in the burden of diseases related to oxidative damage and inflammation, coupled
with the high cost of medication and the side effects of these therapies necessitates a need for more ...
Training needs assessment for forensic nursing in Kenya
(University of Nairobi, 2017)
Introduction: Forensic nursing has not been adopted in Kenya despite the fact that nurses work in settings that require this knowledge. The national Bachelor of Science in nursing syllabus calls for lectures in forensic ...
Socio-demographic and treatment-related variables associated with CD4 cell counts in Kenyan HIV patients on second-line regimens
(KeSoBAP, 2017-08)
Background: CD4 cell response in patients on second-line therapy has not been evaluated in Kenya. Patients failing second-line are changed to third-line, however, the drugs used for third-line are expensive and unavailable. ...