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Now showing items 11-20 of 25
Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole.
(University of Nairobi,, 1983-10)
Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens. One hundred and nine ...
Isolation and identification of Haemophilus ducreyi in a clinical laboratory
(University of Nairobi, 1986-09)
Routine procedures used to isolate Haemophilus ducreyi in a busy laboratory are reported. Identification was based on colony morphology and nutritional and biochemical properties of 120 fresh isolates of H. ducreyi. These ...
Retrospective seroepidemiology of AIDS virus infection in Nairobi populations
(1987)
Among 446 sera from prostitutes in Nairobi, the prevalence of antibody to human immunodeficiency virus (HIV) rose from 4% in 1981 to 61% in 1985. None of 118 men with chancroid seen in 1980 had antibody to HIV compared ...
The clinical diagnosis of genital ulcer disease in men in the tropics
(University of Nairobi,, 1984-06)
Since the clinical diagnosis of genital ulcers without laboratory confirmation is not reliable in developed countries, we postulated that clinical diagnosis alone would be no more reliable in developing countries. A ...
Short-course and single-dose antimicrobial therapy for chancroid in Kenya: studies with rifampin alone and in combination with trimethoprim.
(University of Nairobi,, 1983-08)
Tetracyclines and sulfonamides are no longer effective for the treatment of chancroid in many parts of the world. Rifampin and trimethoprim both possess in vitro activity against Haemophilus ducreyi, the causative agent ...
Prostitutes are a major reservoir of sexually transmitted diseases in Nairobi, Kenya.
(University of Nairobi,, 1985-06)
Prostitutes are a major reservoir of sexually transmitted diseases in many developing nations. In Nairobi we found that 16%, 28%, and 46%, respectively, of upper-, middle-, and lower-social strata prostitutes were infected ...
Treatment of gonorrhea with single-dose thiamphenicol in Kenya
(University of Nairobi,, 1984-12)
The efficacy of a single 2.5-g dose of thiamphenicol against infection with penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) or non-penicillinase-producing strains (non-PPNG) was studied in a two-phase ...
Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase-positive Haemophilus ducreyi infection.
(University of Nairobi,, 1982-09)
Multiresistant strains of Haemophilus ducreyi, the aetiological agent of chancroid, are prevalent in Nairobi, Kenya, where tetracyclines and sulphonamides are no longer very effective in the treatment of chancroid. The ...
Single-dose therapy of chancroid with trimethoprim-sulfametrole
(University of Nairobi,, 1983-07)
We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone ...
Clinical and microbiologic studies of genital ulcers in Kenyan women.
(University of Nairobi,, 1985-12)
The etiology of genital ulcers in women in tropical regions is poorly understood. Eighty-nine women, presenting to a sexually transmitted disease clinic in Nairobi (Kenya) with a primary complaint of genital ulcers, were ...