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Now showing items 11-20 of 21
Human brain and placental choline acetyltransferase: purification and properties.
(1975)
Choline acetyltransferase (EC 2.3.1.6) catalyzes the biosynthesis of acetylcholine according to the following chemical equation: acetyl-CoA + choline in equilibrium to acetylcholine + CoA. In addition to nervous tissue, ...
Biliary excretion of colchicine in newborn rats.
(1975)
The 24-hr LD50 of colchicine in newborn rats is 0.24 mg/kg, which is about 1/10 that observed in the adult. The 24-hr LD50 of colchicine was relatively constant in rats over 25 days of age. In an attempt to determine the ...
Involvement of Central adrenergic mechanisms in the induction of cardiac arrhythmias by aconitine nitrate administered intraventricularly
(1975)
Aconitine, 10 mug, administered intraventricularly in cats produced cardiae arrhythmias. Intraventricular administration of phenoxybenzamine, propranolol and practolol abolishes the centrally induced cardiac arrhythmias. ...
Bovine liver dihydrofolate reductase: purification and properties of the enzyme
(1975)
A purification procedure is reported for obtaining bovine liver dihydrofolate reductase in high yield and amounts of 100-200 mg. A key step in the procedure is the use of an affinity gel prepared by coupling pteroyl-L-lysine ...
Effects of chronic exposure to stressors on avoidance-escape behavior and on brain norepinephrine.
(1975)
A single exposure to a severe stressor (either cold swim or inescapable shock) impairs subsequent performance in a shuttle avoidance-escape task (1), a deficit attributed to reduction in brain noradrenergic activity produced ...
The cholecystokinin test: an assessment.
(,, 1975)
A cholecystokinin (CCK) test was performed on 13 female patients who were thought to be having attacks of gallbladder pain and in whom at least one cholecystogram had been normal. In 10 of these patients the CCK test was ...
The effect of penta-gastrin and cholecystokinin on radiological gastro-oesophageal competence.
(, 1975)
Fourteen patients with clinically obvious gastro-oesophageal reflux were examined by conventional barium meal radiology. Neither exogenous penta-gastrin nor cholecystokinin appeared to influence the radiological competence ...
Some characteristics of two azoreductase systems in rat liver. Relevance to the activity of 2-[4'-di(2″-bromopropyl)-aminophenylazo]benzoic acid (CB10-252), a compound possessing latent cytotoxic activity
(1975)
The system involved in the reduction of 2-[4'-di(2″-bromopropyl)aminophenylazo]benzoic acid (CB10-252), an agent designed for treating primary liver cell cancer, has been demonstrated to be localised mainly in the 108 000 ...
The effects of the continuous administration of N,N-dimethyl-4-phenylazoaniline (DAB) on the activities and the inducibilities of some drug-metabolizing enzymes in rat liver
(University of Nairobi, 1975)
1) The effect of feeding a relatively low-protein diet containing 0.06 % DAB for 29 weeks on the activity of DAB-azoreductase, nitroreductase (p-nitrobenzoic acid), N-oxidase (N,N-dimethylaniline), N-demethylase (DAB), ...
An outbreak of arsenic and toxaphene poisoning in Kenyan cattle
(University of Nairobi, 1975)
In a case of poisoning involving 70 cattle analysis of specimens obtained during post mortem examination showed that the toxic substances were arsenic and toxaphene. This was consistent with both the clinical and post ...