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Response of a sexually transmitted infection epidemic to a treatment and prevention programme in Nairobi, Kenya.
(2002)
Although it seems possible in a developing country context such as Kenya, given appropriate inputs and a sound approach, to shift a sexually transmitted disease (STI) epidemic from phase II to III, it is not entirely clear ...
Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts
(2000)
In Kenya, the median incubation time to AIDS in seroconverting sex workers is 4 years;
this incubation time is specific to female sex workers.We studied the influence of acute sexually transmitted infections (STIs) on ...
Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort
(2008)
OBJECTIVE:
A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed ...
The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol
(2009)
The objectives are to compare the effectiveness of cell phone-supported SMS
messaging to standard care on adherence, quality of life, retention, and mortality in a population
receiving antiretroviral therapy (ART) in ...
Anal and dry sex in commercial sex work, and relation to risk for sexually transmitted infections and HIV in Meru, Kenya
(2006)
To examine the practices of anal intercourse and dry sex within a cohort of female sex workers (FSWs) in Kenya, focusing on the prevalence and perceived risk of the practices, demographic and behavioural correlates, and ...
Associations of sexual risk taking among Kenyan female sex workers after enrollment in an HIV-1 prevention trial.
(2005-03)
BACKGROUND:
Female sex workers (FSWs) often lack the ability to negotiate safer sex and are at high risk for HIV-1 infection and sexually transmitted infections (STIs).
METHODS:
Seronegative FSWs were enrolled in an ...
Coinfection with herpes simplex virus type 2 is associated with reduced HIV-specific T cell responses and systemic immune activation.
(University of Nairobi,, 2008)
BACKGROUND:
Chronic coinfection with herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) has been associated with an increased HIV viral load and more rapid disease progression, perhaps related to ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...
Mucosal Neisseria gonorrhoeae coinfection during HIV acquisition is associated with enhanced systemic HIV-specific CD8 T-cell responses
(2008)
Background: The host immune response against mucosally acquired pathogens may be
influenced by the mucosal immune milieu during acquisition. As Neisseria gonorrhoeae
can impair dendritic cell and T-cell immune function, ...
The impact of pre-exposure prophylaxis (PrEP) on HIV epidemics in Africa and India: a simulation study.
(2008-05)
In this study, condoms were found to be a necessary addition and not a substitute to pre-exposure prophylaxis (PrEP). This, once again. underscores behaviour modification as important in the fight against HIV transmission. ...