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Combinatorial prevention of HIV transmission in women: the case for a vaginal microbicide.
(University of Nairobi, 2011-07)
Women are now becoming pivotal in the epidemiological spread of HIV infection throughout the world, especially in developing countries, where heterosexual transmission accounts for more than 80% of all new HIV infections. ...
Inhibition of double-stranded RNA-dependent protein kinase strongly decreases cytokine production and release in peripheral blood mononuclear cells from patients with Alzheimer's disease.
(University of Nairobi, 2010)
Alzheimer's disease (AD), a neurodegenerative disorder, is the most common form of dementia in the elderly individuals. Among the pathogenic mechanisms in AD, chronic systemic inflammation is described and characterized ...
Neuronal hypertrophy and mast cells in histologically negative, clinically diagnosed acute appendicitis: a quantitative immunophenotypical analysis.
(University of Nairobi, 2010)
INTRODUCTION AND AIM:
In about 20-25% of appendicectomies performed for clinically suspected acute appendicitis, definite morphological changes are lacking on histopathological examination. The present study was done ...
Engineered reversal of drug resistance in cancer cells--metastases suppressor factors as change agents.
(University of Nairobi, 2013)
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that ...
Osteitis of the fourth metatarsal caused by a date palm thorn in a child: why the dorsum of the foot is the most commonly injured site.
(University of Nairobi, 2013-01)
The palms are frequent in the region of eastern Morocco. An insidious onset of a lytic lesion in the base of the fourth metatarsal caused by a date palm thorn in a 20-year-old patient is presented. An untreated embedded ...
Maternal HIV-1 disease progression 18-24 months postdelivery according to antiretroviral prophylaxis regimen (triple-antiretroviral prophylaxis during pregnancy and breastfeeding vs zidovudine/single-dose nevirapine prophylaxis): The Kesho Bora randomized controlled trial
(University of Nairobi, 2012-08)
BACKGROUND:
Antiretroviral (ARV) prophylaxis effectively reduces mother-to-child transmission of human immunodeficiency virus type 1 (HIV). However, it is unclear whether stopping ARVs after breastfeeding cessation ...
Should women with HIV-1 infection breastfeed their infants? It depends on the setting.
(University of Nairobi, 2012)
Breastfeeding is the ideal infant food—it provides both optimal nutrition and numerous factors that contribute to infant immunity, growth, cognition, and health. It also enhances maternal–infant bonding and child-spacing ...
Overcoming Barriers to Family Planning through Integration: Perspectives of HIV-Positive Men in Nyanza Province, Kenya
(2013)
This study explored barriers to and facilitators of using family planning services among HIV-positive men in Nyanza Province, Kenya. From May to June 2010, in-depth interviews were conducted with 30 men receiving care at ...
Is the Pedestrian an Endangered Road User? A Descriptive Account of Pedestrian Musculoskeletal Injuries
(2010)
Background: Trauma is a leading cause of morbidity and mortality in Africa. Road traffic crashes are
causative in majority of these cases. Pedestrians are vulnerable to injury in all types of collisions.
This paper ...
Hiv Postexposure Prophylaxis In An Urban Population Of Female Sex Workers In Nairobi, Kenya.
(University of Nairobi, 2013-02)
OBJECTIVES:
To assess biological and behavioral factors in HIV-uninfected female sex workers (FSWs) accessing postexposure prophylaxis (PEP) and to characterize the circumstances preceding PEP, time to access, and ...