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Trends in clinical characteristics and outcomes of Pre-ART care at a large HIV clinic in Nairobi, Kenya: a retrospective cohort study.
(University of Nairobi, 2016)
BACKGROUND:
The success of antiretroviral therapy in resource-scarce settings is an illustration that complex healthcare interventions can be successfully delivered even in fragile health systems. Documenting the success ...
Low risk of proximal tubular dysfunction associated with emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis in men and women.
(University of Nairobi, 2016)
OBJECTIVE:
Tenofovir disoproxil fumarate (TDF) is associated with proximal tubular dysfunction (tubulopathy) when used in the treatment of human immunodeficiency virus (HIV) infection. We evaluated whether TDF causes ...
Bi treatment with hydralazine/nitrates vs. placebo in Africans admitted with acute HEart Failure (BA-HEF).
(University of Nairobi, 2016)
AIMS:
Patients with acute heart failure (HF) in Africa are rarely being treated with a hydralazine/nitrates combination. Therefore the effect of this treatment was studied here.
METHODS AND RESULTS:
The study was ...
Maternal highly active antiretroviral therapy reduces vertical cytomegalovirus transmission but does not reduce breast milk cytomegalovirus levels.
(University of Nairobi, 2016)
To evaluate the impact of highly active antiretroviral therapy (HAART) on CMV transmission and breast milk level in the context of maternal HIV. Specimens from a randomized trial conducted in Nairobi, Kenya between 2003-2005 ...
Perspectives of host faculty and trainees on international visiting faculty to paediatric academic departments in East Africa.
(University of Nairobi, 2016)
BACKGROUND:
Investments in faculty exchanges to build physician workforce capacity are increasing. Little attention has been paid to the expectations of host institution faculty and trainees. This prospective qualitative ...
Spiritual issues of people living and dying with advanced heart failure in Kenya: a qualitative serial interview study.
(University of Nairobi, 2016)
BACKGROUND:
Exploring patients' spiritual issues is vital for informing holistic care. The spiritual concerns of patients living and dying with advanced heart failure in sub-Saharan Africa remains unknown. Our aim was ...
Determinants of Discontinuation of Contraceptive Methods among Women at Kenyatta National Hospital, Kenya
(2016)
Background: Contraceptive use prevalence in Kenya is at 58% according to the 2014 Kenya Demographic Health
Survey. Several factors lead to discontinuation and switch of contraceptives. Discontinuation rate as per ...
Treatment of chronic heart failure in adults at a referral hospital in Kenya: adverse drug reactions and determinants of adherence
(2016)
Background: Chronic Heart Failure is a major health problem with a prevalence of between 1 and 12% in USA and
Europe, and approximately 5.7% in Sub-Saharan Africa, and has socio-economic relevance owing to its high
prevalence, ...
Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort.
(2016)
Broadly neutralizing antibodies (bnAbs) are thought to be a critical component of a protective HIV vaccine. However, designing vaccines immunogens able to elicit bnAbs has proven unsuccessful to date. Understanding the ...
High Rates of Exclusive Breastfeeding in Both Arms of a Peer Counseling Study Promoting EBF Among HIV-Infected Kenyan Women
(2016)
Background: Exclusive breastfeeding (EBF) is recommended for 6 months after delivery as the optimal infant feeding method and is especially important for prevention of mother-to-child HIV transmission (PMTCT). However, EBF ...