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Maternal and perinatal health research priorities beyond 2015: an international survey and prioritization exercise.
(University of Nairobi,, 2014)
Maternal mortality has declined by nearly half since 1990, but over a quarter million women still die every year of causes related to pregnancy and childbirth. Maternal-health related targets are falling short of the 2015 ...
Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction: a pilot randomized controlled trial
(University of Nairobi, 2014)
Background
Environmental enteric dysfunction (EED) is an acquired syndrome of impaired gastrointestinal mucosal barrier function that is thought to play a key role in the pathogenesis of stunting in early life. It has ...
Calcium Channel Blockers for People with Phronic Kidney Disease Requiring Dialysis
(University of Nairobi, 2014)
This is the protocol for a review and there is no abstract. The objectives are as follows:
This review aims to look at the benefits and harms of CCB for people with CKD requiring dialysis.
Measuring fecal testosterone in females and fecal estrogens in males: comparison of RIA and LC/MS/MS methods for wild baboons (Papio cynocephalus)
(University of Nairobi, 2014-05)
The development of non-invasive methods, particularly fecal determination, has made possible the assessment of hormone concentrations in wild animal populations. However, measuring fecal metabolites needs careful validation ...
The Rise and Fall of HIV in High-Prevalence Countries: A Challenge for Mathematical Modeling
(University of Nairobi, 2014-03)
Several countries with generalized, high-prevalence HIV epidemics, mostly in sub-Saharan Africa, have experienced rapid declines in transmission. These HIV epidemics, often with rapid onsets, have generally been attributed ...
Affordable assessment of newborn brain health following perinatal asphyxia in East Africa: a pilot study (728.6)
(University of Nairobi, 2014)
Perinatal asphyxia is a major cause of infant mortality in the developing world with 280,000 deaths per year in sub-Saharan Africa alone. Brain injuries resulting from asphyxia can have detrimental effects on brain function, ...
A Pilot Comparison of Standardized Online Surgical Curricula for Use in Low- and Middle-Income Countries.
(University of Nairobi, 2014-02-12)
IMPORTANCE Surgical conditions are an important component of global disease burden, due in part to critical shortages of adequately trained surgical providers in low- and middle-income countries. OBJECTIVES To assess the ...
Variants in host viral replication cycle genes are associated with heterosexual HIV-1 acquisition in Africans.
(2014-01-23)
OBJECTIVE::
We evaluated genetic variants in 51 candidate genes encoding proteins that interact with HIV-1 during the virus life cycle for association with HIV-1 outcomes in an African cohort.
METHODS::
Using a ...
Developing Clinical Strength-of-Evidence Approach to Define HIV-Associated Malignancies for Cancer Registration in Kenya.
(University of Nairobi, 2014-01-23)
BACKGROUND:
Sub-Saharan Africa cancer registries are beset by an increasing cancer burden further exacerbated by the AIDS epidemic where there are limited capabilities for cancer-AIDS match co-registration. We undertook ...
A multifaceted intervention to reduce rates of catheter-associated urinary tract infections in a resource-limited setting.
(University of Nairobi, 2014-01)
BACKGROUND:
Health care-associated infections such as catheter-associated urinary tract infections (CAUTIs) are prevalent in resource-limited settings. This study was carried out to determine whether a multifaceted ...