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The sensor kinase MprB is required for Rhodococcus equi virulence
(2011)
Rhodococcus equi is a soil bacterium and, like Mycobacterium tuberculosis, a member of the mycolata. Through possession of a virulence plasmid, it has the ability to infect the alveolar macrophages of foals, resulting in ...
Enrichment Of Variations In KIR3DL1/S1 And KIR2DL2/L3 Among H1n1/09 Icu Patients: An Exploratory Study
(University of Nairobi, 2011)
BACKGROUND:
Infection by the pandemic influenza A (H1N1/09) virus resulted in significant pathology among specific ethnic groups worldwide. Natural Killer (NK) cells are important in early innate immune responses to ...
The Shaping Of Modern Human Immune Systems By Multiregional Admixture With Archaic Humans
(University of Nairobi, 2011)
Whole genome comparisons identified introgression from archaic to modern humans. Our analysis of highly polymorphic human leukocyte antigen (HLA) class I, vital immune system components subject to strong balancing selection, ...
Injury to Presentation Delays Among Musculoskeletal Trauma Patients in Uganda
(2011)
Background: Injuries are a common cause of morbidity and mortality in the developing world with
road traffic crashes being especially prevalent. Kampala has no organised pre hospital rescue service
and this causes delays ...
Prevalence of agenesis of flexor digitorum superficialis of the fifth digit in East Africa through clinical examination
(2011)
Introduction
The flexor digitorum superficialis (FDS) is a flexor of the digits of the hand and has been reported to have varying
rates of agenesis. We conducted a study to determine the prevalence of agenesis of the FDS ...
Safety and effectiveness of antiretroviral drugs during pregnancy, delivery and breastfeeding for prevention of mother-to-child transmission of HIV-1: the Kesho Bora Multicentre Collaborative Study rationale, design, and implementation challenges.
(2011)
To evaluate strategies to reduce HIV-1 transmission through breastfeeding, a multicentre study including a nested randomized controlled trial was implemented in five research sites in West, East and South Africa (The Kesho ...