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sssHigh seroprevalence of SARS-CoV-2 but low infection fatality ratio eight months after introduction in Nairobi, Kenya.
(Elsevier Ltd, 2021)
Background: The lower-than-expected COVID-19 morbidity and mortality in Africa has been attributed to multiple factors, including weak surveillance. We estimated the burden of SARS-CoV-2 infections eight months into the ...
Characteristics Associated with Disclosure Status to Sexual Partners among Kenyan Women
(University of Nairobi, 2020)
Background: Kenya has the fourth-largest HIV epidemic across the globe. Disclosure of HIV-positive status plays a critical role in the prevention of HIV transmission. Disclosure, specifically to sexual partners, has been ...
Feasibility of using an Early Warning Score for preterm or low birthweight infants in a low-resource setting.
(University of Nairobi, 2020)
Introduction
Fifteen million babies are born prematurely, before 37 weeks gestational age, globally. More than 80% of these are in sub-Saharan Africa and Asia. 35% of all deaths in the first month of life are due to ...
A diverse collection of B cells responded to HIV infection in infant BG505.
(University of Nairobi, 2021)
Increasing evidence suggests infants develop unique neutralizing antibody (nAb) responses to HIV compared to adults. Here, we dissected the nAb response of an infant whose virus is in clinical trials as a vaccine immunogen, ...
WHO next-generation partograph: revolutionary steps towards individualised labour care.
(University of Nairobi, 2021)
No abstract available
Neurocognition in Kenyan youth at clinical high risk for psychosis
(University of Nairobi, 2021)
Introduction: Cognitive deficits are typically seen in schizophrenia and in the prodrome, and are a major predictor of functional outcomes in patients. In Africa, few studies have investigated neurocognition in psychosis, ...
Stakeholder-engaged research: strategies for the prevention and control of overweight and obesity in Kenya
(University of Nairobi, 2021)
Background: This study was done as part of a larger study that aims to identify the most impactful and cost-effective strategies for the prevention and control of overweight and obesity in Kenya. Our objective was to involve ...
Employing learning health system principles to advance research on severe neonatal and pediatric illness in Kenya.
(BMJ, 2021)
We have worked to develop a Clinical Information Network (CIN) in Kenya as an early form of learning health systems (LHS) focused on paediatric and neonatal care that now spans 22 hospitals. CIN's aim was to examine important ...
Prediction modelling of inpatient neonatal mortality in high-mortality settings.
(BMJ, 2020)
Objective: Prognostic models aid clinical decision making and evaluation of hospital performance. Existing neonatal prognostic models typically use physiological measures that are often not available, such as pulse oximetry ...
Cerebral Small Vessel Disease in Sporadic and Familial Alzheimer Disease
(University of Nairobi, 2021)
Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and neurodegeneration. However, current evidence ...