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Breast milk HIV-1 suppression and decreased transmission: a randomized trial comparing HIVNET012 nevirapine versus short-course zidovudine
(2005)
Objective: To compare the effect of perinatal regimens of short-course nevirapine
(HIVNET012)andzidovudine[Thai-CentersforDiseaseControlandPrevention(CDC)
regimen] on breast milk viral shedding and perinatal transmission ...
Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?
(2005)
Resistance to the antifolate sulfadoxine–pyrimethamine (SP), the current mass-treatment antimalarial drug, is associated with selection of point mutations in dihydrofolate reductase and dihydropteroate synthase. Among these ...
Domestic violence and prevention of mother-to-child transmission of HIV-1
(2006)
Objectives Todeterminetheprevalenceof life-timedomesticviolencebythecurrent
partnerbeforeHIV-1testing,itsimpactontheuptakeofpreventionofmother-to-child
transmission (PMTCT) interventions and frequency after testing.
Design ...
Implementing a hospital based injury surveillance system in Africa: lessons learned
(2008)
A multinational injury surveillance pilot project was carried out in five African countries in the first half of 2007 (Democratic Republic of the Congo, Kenya, Nigeria, Uganda and Zambia). Hospitals were selected in each ...
CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
(2/6/2009)
Background: Clinical laboratory reference intervals have not been established in many African countries, and non-local
intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African ...
Does prospective monitoring improve cataract surgery outcomes in Africa?
(2007-06)
Aims: To determine if prospective monitoring influences cataract surgical outcomes in east Africa.
Methods: A prospective observational study of all routine extracapsular cataract extractions with posterior
chamber lens ...
Population pharmacokinetics of a single daily intramuscular dose of gentamicin in children with severe malnutrition
(2007)
The World Health Organization recommends that all children admitted with severe malnutrition should routinely receive parenteral ampicillin and gentamicin; despite this, mortality remains high. Since this population group ...
The effect of rapid HIV-1 testing on uptake of perinatal HIV-1 interventions: a randomized clinical trial
(2003)
Objective
We examined whether HIV-1 testing using a rapid assay increases the proportion of pregnant women obtaining HIV-1 results and the uptake of perinatal HIV-1 interventions.
Methods
Pregnant women attending ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...