Faculty of Health Sciences (FHS): Recent submissions
Now showing items 241-260 of 10378
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An Interesting Case of Fatal Myasthenic Crisis Probably Induced by the COVID-19 Vaccine
(University of Nairobi, 2022-03)A myasthenic crisis is a severe, life-threatening exacerbation of myasthenia gravis that causes a rapid onset of muscle weakness and fatigue that may result in tetraparesis, dyspnea, respiratory insufficiency, aspiration, ... -
International Pediatric Emergency Medicine and Critical Care Fellow Education: Utilizing Virtual Resuscitation Simulation in Settings With Differing Resources
(University of Nairobi, 2022-02)Pediatric Emergency and Critical Care-Kenya (PECC-Kenya) is an international collaboration between the University of Nairobi and the University of Washington (UW) supporting a combined fellowship program in pediatric ... -
Dynamic Changes in Breast Milk Microbiome in the Early Postpartum Period of Kenyan Women Living With Hiv Are Influenced by Antibiotics but Not Antiretrovirals
(University of Nairobi, 2022)Shared bacteria between maternal breast milk and infant stool, infers that transfer of maternal breast milk microbiota through breastfeeding seeds the establishment of the infant gut microbiome. Whether combination ... -
Improving postpartum hemorrhage care: Policy, practice, and research
(University of Nairobi, 2022-06) -
Rationale for integration of services for diabetes mellitus and diabetic retinopathy in Kenya
(University of Nairobi, 2022-05)Background: Good diabetes mellitus (diabetes) and diabetic retinopathy (DR) management depends on the strength of the health system, prompting us to conduct a health system assessment for diabetes and DR in Kenya. We used ... -
Cross-sectional Study to Predict Subnational Levels of Health Workers' Knowledge About Severe Malaria Treatment in Kenya
(University of Nairobi, 2022)Objectives: This study applied a Bayesian hierarchical ecological spatial model beyond predictor analysis to test for the best fitting spatial effects model to predict subnational levels of health workers' knowledge of ... -
The prevalance of binge eating disorder and associated psychiatric and substance use disorders in a student population in Kenya - towards a public health approach
(University of Nairobi, 2022-02)Introduction: Kenya in particular and Africa in general lack data on Binge Eating Disorder (BED). The overarching objective of this study is to fill that gap. Kenyans may not be aware that BED exists when a "very good" ... -
In vitro anticoccidial activity of nanoencapsulated bromelain against Eimeria spp. oocysts isolated from goats in Kenya
(University of Nairobi, 2022-02)Background and aim: The emergence of drug-resistant strains of Eimeria spp. calls for the development of novel anticoccidial drugs. Plant extracts provide a possible natural source for such drugs. This study aimed to ... -
Demographic, Clinical, and Co-Morbidity Characteristics of COVID-19 Patients: A Retrospective Cohort from a Tertiary Hospital in Kenya
(University of Nairobi, 2021-04)Introduction: The first documented case of COVID-19 in Kenya was recorded March of 2020. Co-morbidities including hypertension and diabetes have been associated with increased morbidity, hospitalization, and mortality among ... -
Effect of Finishing Protocols and Staining Solutions on Color Stability of Dental Resin Composites
(University of Nairobi, 2022)Objective: The objective of this study was to evaluate the effect of finishing protocol and exposure to staining solutions on color stability of dental resin composites. Materials and methods: A nanofill and microhybrid ... -
Pairwise Joint Modeling of Clustered and High-dimensional Outcomes With Covariate Missingness in Pediatric Pneumonia Care
(University of Nairobi, 2022)Multiple outcomes reflecting different aspects of routine care are a common phenomenon in health care research. A common approach of handling such outcomes is multiple univariate analyses, an approach which does not allow ... -
Progress on the national action plan of Pakistan on antimicrobial resistance (AMR): a narrative review and the implications
(University of Nairobi, 2022-01)Introduction: The emergence of antimicrobial resistance (AMR) is a threat to public health. In 2015, the World Health Organization (WHO) introduced a global action plan to tackle AMR in the World Health Assembly. Pakistan's ... -
Effects of cytochrome P450 2B6 and constitutive androstane receptor genetic variation on Efavirenz plasma concentrations among HIV patients in Kenya
(University of Nairobi, 2022-03)The effects of genetic variation of cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) on efavirenz (EFV) plasma concentration was evaluated among 312 HIV patients in Nairobi Kenya. The EFV plasma ... -
Prevalence of Trachomatous Trichiasis in Ten Evaluation Units of Embu and Kitui Counties, Kenya
(University of Nairobi, 2022-01)Background: Late-stage blinding sequalae of trachoma such as trachomatous trichiasis (TT) typically take decades to develop and often do so in the absence of ongoing ocular Chlamydia trachomatis infection. This suggests ... -
High Level of Pre-Treatment HIV-1 Drug Resistance and Its Association with HLA Class I-Mediated Restriction in the Pumwani Sex Worker Cohort
(University of Nairobi, 2022-01)Background: We analyzed the prevalence of pre-antiretroviral therapy (ART) drug resistance mutations (DRMs) in a Kenyan population. We also examined whether host HLA class I genes influence the development of pre-ART ... -
Global article collection: essential reads from around the world
(University of Nairobi, 2022-01) -
Psychological Experiences of Caregivers of Adolescents Diagnosed With Substance Use Disorder Attending a Youth Centre in a Low-resource Setting
(University of Nairobi, 2022)Caregivers, whether a biological parent, adoptive parent, or a relative such as a grandparent, of adolescent with substance use disorder (SUD) undergo immense psychological and social strains, as they have to deal with ... -
CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study
(University of Nairobi, 2022-07)Background: Tuberculosis remains a leading cause of global mortality, especially for adults and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum-based assays are needed to improve tuberculosis ... -
In Vitro Anti-hiv and Cytotoxic Effects of Pure Compounds Isolated From Croton Macrostachyus Hochst. Ex Delile
(University of Nairobi, 2022)Croton macrostachyus is an important plant in traditional African medicine, widely utilized to treat a variety of diseases. In Kenya, HIV-infected patients use leaf and root decoctions of the plant as a cure for cough, ... -
Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate
(University of Nairobi, 2022-05)Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and ...