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Now showing items 161-170 of 17363
Evaluation of the adjuvanticity of artemisinin with soluble Leishmania major antigens in BALB/c mice
(2009)
Objective
To determine the adjuvant potential of artemisinin with a soluble leishmanial antigen in vaccinating BALB/c mice.
Methods
Seventy two female BALB/c mice were randomly assigned into six groups. The mice ...
Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya.
(University of Nairobi, 2013)
BACKGROUND:
There are a number of practical and ethical issues raised in school-based health research, particularly those related to obtaining consent from parents and assent from children. One approach to developing, ...
Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
(University of nairobi, 2010)
Abstract
BACKGROUND:
We conducted a double-blind, randomized, placebo-controlled Phase I study of a recombinant replication-defective adenovirus type 5 (rAd5) vector expressing HIV-1 Gag and Pol from subtype B and Env ...
In vivo screening of antimalarial activity of Acacia mellifera (Benth) (Leguminosae) on Plasmodium berghei in mice.
(2007)
The activities of total extracts and lupane triterpenes, isolated from the stem bark of Acacia mellifera, were evaluated against Plasmodium berghei strain ANKA in a female Swiss mouse model. Five isolated compounds and the ...
Mortality Projection: Curve Fitting And Linear Regression
(2011)
This study was aimed at predicting future mortality rates given two main scenarios. The first is in the
case where there is a body of mortality tables from the past and the second is in the case where such a
database ...
Aflatoxicosis: health implications.
(University of Nairobi, 2005-06)
No abstract available
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
(2012)
BACKGROUND:
Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated ...
Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis
(2013)
Previous small series have suggested that acute myeloid leukemia with t(8;16) is a distinct morphologic and clinical entity associated with poor prognosis. We describe 18 patients with t(8;16) AML, including their clinical, ...