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The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1 infected women and their infants
(2009)
Objective—Cytomegalovirus (CMV) is an important pathogen in healthy neonates and individuals
with human immunodeficiency virus (HIV-1). The objective of this study was to determine whether
the detection of CMV DNA (CMV ...
Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children
(2009)
Background: As highly active antiretroviral therapy (HAART) becomes increasingly available to African children,
it is important to evaluate simple and feasible methods of improving adherence in order to maximize benefits ...
Risk factors for neonatal conjunctivitis in babies of HIV-1 infected mothers
(2009)
Purpose—To determine the prevalence and correlates of neonatal conjunctivitis in infants born
to human immunodeficiency virus type 1 (HIV-1) infected mothers.
Methods—This was a nested case-control study within a perinatal ...
Pediatric HIV-1 in Kenya:pattern and correlates of viral load and association with mortality
(2009)
Background—There is limited information regarding the pattern and correlates of viral replication
in vertically HIV-1–infected children and its role on their outcomes in resource-limited settings.
Methods—HIV-1–infected ...
Comparison of CD4 Cell Count, Viral Load, and other markers for the prediction of mortality among HIV-1–Infected Kenyan pregnant women
(2009)
Background. There are limited data regarding the relative merits of biomarkers as predictors of mortality or time
to initiation of antiretroviral therapy (ART).
Methods. We evaluated the usefulness of the CD4 cell count, ...
Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition
(2009)
Infants infected with HIV-1 after the first month of life have a lower viral
set-point and slower disease progression than infants infected before 1
month. We investigated the kinetics of HIV-1-specific CD8+ T ...
HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission.
(2009)
Breast-feeding by infants exposed to human immunodeficiency virus type 1 (HIV-1) provides an opportunity to assess the role played by repeated HIV-1 exposure in eliciting HIV-1-specific immunity and in defining whether ...
Performance of Clinical Algorithms for HIV-1 Diagnosis and Antiretroviral Initiation among HIV-1-Exposed Children Aged Less Than 18 Months in Kenya
(2009-04)
Background
Ninety percent of HIV-1-infected children live in sub-Saharan Africa. In the absence of diagnosis and antiretroviral therapy (ART), approximately 50% die before 2 years.
Methods
We evaluated sensitivity ...
Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children: a randomized clinical trial
(2009-06-24)
Abstract
Background
As highly active antiretroviral therapy (HAART) becomes increasingly available to African children, it ...