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Bacterial vaginosis, HIV serostatus and T-cell subset distribution in a cohort of East African commercial sex workers: retrospective analysis
(2012)
Although bacterial vaginosis is a known correlate of HIV infection, no previous studies have investigated whether women defined as HIV-exposed seronegative (HESN) are less likely to have bacterial vaginosis. Little is known ...
Genital inflammation predicts HIV-1 shedding independent of plasma viral load and systemic inflammation
(2012)
In women, genital HIV-1 RNA levels predict the risk of
HIV-1 transmission independent of plasma viral load. To better
understand the factors that contribute to genital HIV-1 shedding, we
evaluated the relationships ...
Association between participant self-report and biological outcomes used to measure sexual risk behavior in HIV-1- seropositive female sex workers in Mombasa, Kenya
(2012)
Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults.
METHODS:
We conducted a prospective cohort ...
Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV Exposed, seronegative female sex workers in Kenya
(2012)
Identifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune ...
Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case–control study
(2012)
Although antiretroviral therapy (ART) prolongs life and reduces infectiousness, in some contexts, it has been associated with increased sexual risk taking.
Design
Retrospective case–control study.
Setting
...
Background Morbidity In HIV Vaccine Trial Participants From Various Geographic Regions As Assessed By Unsolicited Adverse Events
(University of Nairobi, 2012-05)
BACKGROUND:
Recently, more clinical trials are being conducted in Africa and Asia, therefore, background morbidity in the respective populations is of interest. Between 2000 and 2007, the International AIDS Vaccine ...
Factors associated with resumption of sex before complete wound healing in circumcised HIV-positive and HIV-negative men in Kisumu, Kenya.
(University of Nairobi, 2012-12)
BACKGROUND:: We evaluated time-to-resumption of sex in relation to wound healing following circumcision of adult males. The purpose was to assess factors associated with adherence to the WHO recommendation of 42-days ...
Selection, Phenotyping and Identification of Acid and Hydrogen Peroxide Producing Bacteria from Vaginal Samples of Canadian and East African Women
(2012)
The common but poorly understood condition known as bacterial vaginosis (BV) increases vulnerability to HIV infection and is associated with the absence of H(2)O(2)-producing Lactobacillus. Vaginal lactic acid bacteria ...
An Integrated approach for antiretroviral adherence and secondary HIVtransmission risk-reductionsupport by nurses in Kenya
(2012)
Ongoing antiretroviral therapy (ART) adherence
and secondary HIV transmission-risk reduction
(positive prevention) support are needed in resourcelimited
settings.We evaluated a nurse-delivered counseling
intervention ...
HIV-1 Clade D Is Associated with Increased Rates of CD4 Decline in a Kenyan Cohort
(2012)
HIV-1 is grouped phylogenetically into clades, which may impact rates of HIV-1 disease progression. Clade D infection in
particular has been shown to be more pathogenic. Here we confirm in a Nairobi-based prospective ...