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Now showing items 11-20 of 23
The Effect Of Hormonal Contraception On Genital Tract Shedding Of Hiv-1.aids
(University of Nairobi, 2004-01-23)
OBJECTIVE: A previous cross-sectional study reported that hormonal contraception may be associated with increased infectivity in HIV-1 infected women. We conducted a prospective study to determine if cervical shedding of ...
A Prospective Study Of Risk Factors For Herpes Simplex Virus Type 2 Acquisition Among High-risk Hiv-1 Seronegative Women In Kenya
(University of Nairobi, 2009)
Objectives: Several studies have demonstrated an association between herpes simplex virus type 2 (HSV-2) and HIV-1, but available data on risk factors for HSV-2 acquisition are limited. The objective of this analysis was ...
Distinct but related human immunodeficiency virus type 1 variant populations in genital secretions and blood
(1996)
For a HIV vaccine to be effective, it will be essential that it protect against the virus variants to which individuals are most frequently exposed. HIV-1 is predominantly a sexually acquired virus, thus, variants in genital ...
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
(2004)
BACKGROUND:
Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. ...
Vitamin A deficiency and the acute phase response among HIV-1-infected and -uninfected women in Kenya
(2002)
Among HIV-1-infected individuals, vitamin A deficiency has been associated with faster disease progression and greater infectivity in observational studies, but randomized clinical trials have shown no effect of vitamin A ...
Studies of human immunodeficiency virus type 1 mucosal viral shedding and transmission in Kenya.
(University of Nairobi., 1999-05)
If human immunodeficiency virus type 1 (HIV-1) vaccines are to be highly effective, it is essential to understand the virologic factors that contribute to HIV-1 transmission. It is likely that transmission is determined, ...
Cell-free human immunodeficiency virus type 1 in breast milk
(University of Nairobi, 1998)
Breast-feeding may be an important route of human immunodeficiency virus type 1 (HIV-1) vertical transmission in settings where it is routinely practiced. To define the prevalence and quantity of HIV-1 in cell-free breast ...
The Effect Of Treatment Of Vaginal Infections On Shedding Of Human Immunodeficiency Virus Type 1
(University of Nairobi, 2001)
We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes ...
Human immunodeficiency virus type 1-infected cells in breast milk: association with immunosuppression and vitamin A deficiency
(1995-12)
Breast milk samples from human immunodeficiency virus type 1 (HIV-1)-seropositive women were analyzed by polymerase chain reaction to determine the prevalence and determinants of HIV-1-infected cells in breast milk. Breast ...
No evidence for rapid subtype C spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate
(2005)
There are multiple subtypes of HIV-1 circulating worldwide, but recently, subtype C has become highly prevalent, particularly in certain geographic regions. It is unclear whether the dominance of subtype C or other subtypes ...