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Breastfeeding and immunity to intestinal infections
(1995)
The purpose of this study was to compare immune response in breast and non breastfed children presenting with diarrhoea at Paediatric Observation Ward, Kenyatta National Hospital (KNH-POW) and Maternal and Child Health ...
The importance of core groups in the epidemiology and control of HIV-1 infection
(1991)
In Africa, HIV transmission occurs mainly through heterosexual intercourse. High-frequency transmitter core groups are key to the epidemiology of HIV-1 and STD on the continent. The rapid growth of the HIV-1 epidemic in ...
Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection
(1995)
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several ...
Stable antenatal HIV-1 seroprevalence with high population mobility and marked seroprevalence variation among sentinel sites within Nairobi, Kenya.
(1999)
Objectives: To monitor and analyse trends in HIV-1 seroprevalence among
antenatal women in Nairobi, Kenya.
Design: Six sequential surveys were carried out among antenatal clinic attenders at
four Nairobi City Council ...
Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission
(University of Nairobi, 1998-03)
Major histocompatibility complex (MHC) gene products are expressed on human immunodeficiency virus (HIV)-infected cells and incorporated into the lipid envelope of HIV virions. Macaques immunized with human MHC gene products ...
Increased Risk of infection with Human Immunodeficiency Virus Type 1 among Uncircumcised Men Presenting with Genital Ulcer Disease in Kenya Clin
(University of Nairobi, 1996-09)
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. ...
Risk factors for postnatal mother-child transmission of HIV-1.
(2000)
OBJECTIVE:
To identify factors affecting HIV-1 breastfeeding transmission.
DESIGN:
Longitudinal observational cohort study.
METHODS:
HIV-1 seropositive pregnant women and seronegative controls were enrolled ...