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Anti-plasmodial Activities Of Flavonoids From Erythrina Sacleuxii
(University of Nairobi, 2006-02)
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic ...
Antiplasmodial activity of compounds from the surface exudates of Senecio roseiflorus
(University of Nairobi, 2013-02)
From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic ...
Antiparasitic and anticancer carvotacetone derivatives from Sphaeranthus bullatus
(2012-09)
The 1:1 MeOH/CH2Cl2 extract of aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7µg/ml) and chloroquine resistant W2 (IC50 ...
Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti
(University of Nairobi, 2003-10)
A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 µg ml−1 at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, ...
Antimicrobial flavonoids from the stem bark of Erythrina burttii
(University of Nairobi, 2005-07)
The chloroform extract of the stem bark of Erythrina burttii showed antifungal and antibacterial activities using the disk diffusion method. Flavonoids were identified as the active principles. Activities were observed ...
7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata
(2005-03)
From the acetone extract of the roots of Derris trifoliata an isoflavonoid derivative, named 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isoflavonoids (the sub-class is ...
Three ent-trachylobane diterpenes from the leaf exudates of Psiadia punctulata
(Elsevier, 2006-07)
Three ent-trachylobane diterpenes have been isolated from the leaf exudates of Psiadia punctulata and characterised as 6α,17,19-ent-trachylobantriol; 2α,18,19-ent-trachylobantriol; and 2β,6α,18,19-ent-trachylobantetraol. ...
Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata
(2006-05)
The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a ...