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A xanthone and a phenylanthraquinone from the roots of Bulbine frutescens, and the revision of six seco-anthraquinones into xanthones
(University of Nairobi, 2014)
Phytochemical investigation of the dichloromethane/methanol (1:1) extract of the roots of Bulbine frutescens led to the isolation of a new xanthone, 8-hydroxy-6-methylxanthone-1-carboxylic acid (1) and a new phenylanthraquinone, ...
Four isoflavones from the stem bark of erythrina sacleuxii
(University of Nairobi, 1998-09-03)
From the stem bark of Erythrina sacleuxii four new isoflavones were isolated and characterized as 5,7-dihydroxy-2′,4′,5′-trimethoxyisoflavone (trivial name, 7-demethylrobustigenin), 5,7-dihydroxy-4′-methoxy3′-(3-methylbu ...
Antiplasmodial Flavonoids from Erythrina sacleuxii
(University of Nairobi, 2006-02)
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic ...
Antiplasmodial and larvicidal flavonoids from Derris trifoliata
(2009)
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new
flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin
and rotenone ...
6α-Hydroxy-α-toxicarol and (+)-tephrodin with antiplasmodial activities from Tephrosia species
(Elsevier, 2014)
The CH2Cl2/MeOH (1:1) extract of the roots of Tephrosia villosa showed good antiplasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values ...
Antimicrobial flavonoids and diterpenoids from Dodonaea angustifolia
(University of Nairobi, 2014-03)
The surface exudates of the leaves of Dodonaea angustifolia from Ngong forest population (6 km from Nairobi city center, Kenya) demonstrated antimicrobial activity against Gram-negative (Escherichia coli), Gram-positive ...
3-Hydroxyisoflavanones from the stem bark of Dalbergia melanoxylon: Isolation, antimycobacterial evaluation and molecular docking studies
(University of Nairobi, 2013-11)
Two new 3-hydroxyisoflavanones, (S)-3,4′,5-trihydroxy-2′,7-dimethoxy-3′-prenylisoflavanone (trivial name kenusanone F 7-methyl ether) and (S)-3,5-dihydroxy-2′,7-dimethoxy-2″,2″-dimethylpyrano[5″,6″:3′,4′]isoflavanone ...
Antiplasmodial, cytotoxicity and phytochemical constituents of four maytenus species used in traditional medicine in Kenya
(2017)
Background: In Kenya, several species of the genus Maytenus are used in traditional medicine to treat many diseases including malaria. In this study, phytochemical constituents and extracts of Maytenus undata, M. ...
8-Methoxyneorautenol and radical scavenging flavonoids from Erythrina abyssinica
(2009)
A new pterocarpan (named 8-methoxyneorautenol) was isolated from the acetone extract of the
root bark of Erythrina abyssinica. In addition, the known isoflavonoid derivatives eryvarin L, erycristagallin and
shinpterocarpin ...