Browsing Faculty of Health Sciences (FHS) by Author "Nagelkerke, N J"

Now showing items 1-7 of 7

    • Hiv-specific Cd8+ T-cell Proliferation Is Prospectively Associated With Delayed Disease Progression. 

      McKinnon, LR Kaul R, Kimani J, Nagelkerke NJ, Wachihi C, Fowke KR, Ball TB, Plummer FA.; Kaul, R; Kimani, J; Nagelkerke, N J; Wachihi, C; Fowke, KR; Ball, T B; Plummer, FA. (University of NairobiDepartment of Medical Microbiology, 2012-03)
      Human immunodeficiency virus (HIV)-specific CD8(+) T-cell proliferation is consistently correlated with enhanced host HIV immune control, but whether proliferative responses are a cause or consequence of immune protection ...

    • The HLA A2/6802 Supertype Is Associated With Reduced Risk Of Perinatal Human Immunodeficiency Virus Type 1 Transmission. J I 

      Macdonald, K S; Embree, J E; Nagelkerke, N J; Castillo, J; Ramhadin, S; Njenga, S; Oyug, J; Ndinya-Achola, JO; Barber, B H; Bwayo, JJ; Plummer, F A (University of NairobiInstitute of Tropica and Infectious Diseases(UNITID), 2001-02-01)
      Certain HLAs may, in part, account for differences in human immunodeficiency virus type 1 (HIV-1) susceptibility by presenting conserved immunogenic epitopes for T cell recognition. The HLA supertype A2/6802 is associated ...

    • Human Leucocyte Antigen Supertypes And Immune Susceptibility To Hiv-1, Implications 

      Macdonald K, S; Matukas, L; Embree, J E; Fowke, K; Kimani, J; Nagelkerke, N J; Oyugi, J; Kiama, P; Kaul, R; Luscher, M A; Rowland-jones, S; Ndinya-Achola, JO; Ngugi, Elizabeth N; Plummer, F A; Bwayo, JJ (University of NairobiDepartment of Medical Microbiology, 2001-11-01)

    • The impact of pre-exposure prophylaxis (PrEP) on HIV epidemics in Africa and India: a simulation study. 

      Ngugi, Elizabeth N; Vissers, D C; Voeten, H A; Nagelkerke, N J; Habbema, J D; Vlas, S J (Department of Community HeaLth, College of HeaLth Sciences, University of Nairobi, Nairobi, Kenya, 2008-05)
      In this study, condoms were found to be a necessary addition and not a substitute to pre-exposure prophylaxis (PrEP). This, once again. underscores behaviour modification as important in the fight against HIV transmission. ...

    • Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection. 

      Kimani, J; Oyugi, J; Njagi, Elizabeth N; Wade, J; Krausa, P; Rowland-Jones, S; Ngugi, E; Bwayo, JJ; Plummer, FA; Luscher, M A; Brunham, R C; MacDonald, K S; Fowke, K R; Dunand, V A; Nagelkerke, N J; Ball, T B; Gaur, L K (Department of Medicine, 2000-05)
      Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T cell recognition, may, in part, account for the observed differences in human immunodeficiency virus type 1 (HIV-1) susceptibility. To ...

    • Tuberculosis and the HIV epidemic: increasing annual risk of tuberculous infection in Kenya, 1986-1996. 

      Odhiambo, J A; Borgdorff, M W; Kiambih, F M; Kibuga, D K; Kwamanga, D O; Ng'ang'a, L; Agwanda, R; Kalisvaart, N A; Misljenovic, O; Nagelkerke, N J; Bosman, M (University of NairobiCollege of Health Sciences,University of Nairobi, 1999-07)
      OBJECTIVES: The purpose of this study was to assess the impact of the increased incidence of tuberculosis (TB) due to HIV infection on the risk of TB infection in schoolchildren. METHODS: Tuberculin surveys were carried ...

    • Vitamin A And Risk Of HIV-1 Seroconversion Among Kenyan Men With Genital Ulcers. 

      Macdonald, K S; Malonza, I; Chen, D K; Nagelkerke, N J; Nasio, J M; Ndinya-Achola, JO; Bwayo, JJ; Sitar, D S; Aoki, F Y (University of NairobiSchool of Public Health Centre for HIV Prevention and Research, 2001-03-30)
      Background: Vitamin A is involved in normal immune function and the maintenance of mucosal integrity through complex effects on cellular differentiation. Objective: We sought to determine whether serum vitamin A levels ...