Search
Now showing items 1-6 of 6
Medication diaries do not improve outcomes with highly active antiretroviral therapy in Kenyan children
(2009)
Background: As highly active antiretroviral therapy (HAART) becomes increasingly available to African children,
it is important to evaluate simple and feasible methods of improving adherence in order to maximize benefits ...
Pediatric HIV-1 in Kenya:pattern and correlates of viral load and association with mortality
(2009)
Background—There is limited information regarding the pattern and correlates of viral replication
in vertically HIV-1–infected children and its role on their outcomes in resource-limited settings.
Methods—HIV-1–infected ...
Analysis of the Percentage of Human Immunodeficiency Virus Type 1 Sequences That Are Hypermutated and Markers of Disease Progression in a Longitudinal Cohort, Including One Individual with a Partially Defective Vif
(University of Nairobi, 2009-08)
Hypermutation, the introduction of excessive G-to-A substitutions by host proteins in the APOBEC family, can impair replication of the human immunodeficiency virus (HIV). Because hypermutation represents a potential antiviral ...
Comparison of CD4 Cell Count, Viral Load, and other markers for the prediction of mortality among HIV-1–Infected Kenyan pregnant women
(2009)
Background. There are limited data regarding the relative merits of biomarkers as predictors of mortality or time
to initiation of antiretroviral therapy (ART).
Methods. We evaluated the usefulness of the CD4 cell count, ...
Temporal analysis of HIV envelope sequence evolution and antibody escape in a subtype A-infected individual with a broad neutralizing antibody response
(2009)
The origin of broadly neutralizing HIV-specific antibodies and their relation to HIV evolution are not well
defined. Here we examined virus evolution and neutralizing antibody escape in a subtype A infected
individual ...
Acute cytomegalovirus infection in Kenyan HIV-infected infants
(2009)
Objective: Cytomegalovirus (CMV) coinfection may influence HIV-1 disease progression
during infancy. Our aim was to describe the incidence of CMV infection
and the kinetics of viral replication in Kenyan HIV-infected and ...