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Now showing items 1-9 of 9
The importance of core groups in the epidemiology and control of HIV-1 infection
(1991)
In Africa, HIV transmission occurs mainly through heterosexual intercourse. High-frequency transmitter core groups are key to the epidemiology of HIV-1 and STD on the continent. The rapid growth of the HIV-1 epidemic in ...
Isoniazid preventive therapy for tuberculosis in HIV-1-infected adults: results of a randomized controlled trial
(1997)
OBJECTIVES:
To determine the efficacy of isoniazid 300 mg daily for 6 months in the prevention of tuberculosis in HIV-1-infected adults and to determine whether tuberculosis preventive therapy prolongs survival in ...
Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection
(1995)
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several ...
Human immunodeficiency virus infection among high-risk seronegative prostitutes in Nairobi
(1993)
To determine the frequency and duration of antibody-negative human immunodeficiency virus (HIV) infection among heterosexually exposed African women, 56 HIV-seronegative female prostitutes in Nairobi were studied. Polymerase ...
Stable antenatal HIV-1 seroprevalence with high population mobility and marked seroprevalence variation among sentinel sites within Nairobi, Kenya.
(1999)
Objectives: To monitor and analyse trends in HIV-1 seroprevalence among
antenatal women in Nairobi, Kenya.
Design: Six sequential surveys were carried out among antenatal clinic attenders at
four Nairobi City Council ...
Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya
(1996)
BACKGROUND:
There is indirect evidence that HIV-1 exposure does not inevitably lead to persistent infection. Heterogeneity in susceptibility to infection could be due to protective immunity. The objective of this study ...
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers
(1999)
Objectives: Most HIV-1 transmission is sexual; therefore, immune responses in the
genital mucosa may be important in mediating protection against HIV infection. This
study examined HIV-1-specific mucosal IgA in a cohort ...
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
(University of Nairobi, 1998-11)
Many people who remain persistently seronegative despite frequent HIV exposure have HIV-specific immune responses. The study of these may provide information about mechanisms of natural protective immunity to HIV-1. We ...
Risk factors for genital ulcerations in Kenyan sex workers. The role of human immunodeficiency virus type 1 infection.
(1997)
BACKGROUND AND OBJECTIVES: Genital ulcer disease (GUD) is a major risk factor for human immunodeficiency virus (HIV) transmission. Cross-sectional studies have suggested that HIV infection may itself predispose to genital ...