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Reply to “Male Involvement' in Women and Children's HIV Prevention: Challenges in Definition and Interpretation”
(University of Nairobi, 2011)
Expanding Clinical Medical Training Opportunities at the University of Nairobi: Adapting a Regional Medical Education Model From the WWAMI Program at the University of Washington.
(University of Nairobi, 2014-08)
A major medical education need in Sub-Saharan Africa includes expanding clinical training opportunities to develop health professionals. Medical education expansion is a complicated process that requires significant ...
Mode Of Delivery And Postpartum Hiv-1 Disease Progression And Mortality In A Kenyan Cohort
(University of Nairobi, 2014-08)
There are limited data on the impact of cesarean section delivery on HIV-1 infected women in Sub-Saharan Africa. The purpose of this study was to assess the effect of mode of delivery on HIV-1 disease progression and ...
Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.
Abstract BACKGROUND: Antiretroviral pre-exposure prophylaxis (PrEP), with daily oral tenofovir disoproxil fumarate or tenofovir disoproxil fumarate in combination with emtricitabine, has been shown to be efficacious ...
The Afya Bora Fellowship in Global Health Leadership: dual mentorship to strengthen the next generation of African health leaders
(University of Nairobi, 2015-02)
Program/Project Purpose Mentorship is critical to develop effective leaders. The Afya Bora Fellowship in Global Health Leadership program, a consortium of four African and four U.S. universities formed in 2008, has ...
Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition
(University of Nairobi., 2010-06)
The C868T single nucleotide polymorphism (SNP) in the CD4 receptor encodes an amino acid change that could alter its structure and influence human immunodeficiency virus (HIV-1) infection risk. HIV-1-infected pregnant women ...
Prevalence, perceptions, and correlates of pediatric HIV disclosure in an HIV treatment program in Kenya.
Disclosure to HIV-infected children regarding their diagnosis is important as expanding numbers of HIV-infected children attain adolescence and may become sexually active. In order to define correlates of pediatric disclosure ...
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
Most persons who are infected with human immunodeficiency virus type 1 (HIV-1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated and is associated with increased plasma and genital ...
Herpes simplex virus type 2 suppressive therapy with acyclovir or valacyclovir does not select for specific HIV-1 resistance in HIV-1/HSV-2 dually infected persons.
(Univesity of Nairobi, 2011-01)
Recent in vitro studies suggest that acyclovir may directly inhibit HIV-1 replication and can select for a specific HIV-1 reverse transcriptase mutation (V75I) with concomitant loss of an anti-HIV-1 effect. We tested for ...
Immune response to hepatitis B virus vaccination among HIV-1 infected and uninfected adults in Kenya.
In studies from high-income countries, human immunodeficiency virus type 1 (HIV-1)-infected persons have diminished responses to hepatitis B virus (HBV) vaccination, compared with HIV-1-uninfected persons, but data from ...