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Cofactors for HIV-1 incidence during pregnancy and postpartum period.
(2010-10)
OBJECTIVES:
to estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.
DESIGN:
retrospective study among women who were HIV seronegative during pregnancy.
METHODS:
mothers ...
Long-term Virologic Response and Genotypic Resistance Mutations in HIV-1 Infected Kenyan Children on Combination Antiretroviral Therapy.
(University of Nairobi., 2012-11-28)
Backround: HIV-infected children may require the use of combination antiretroviral treatment (cART) into adulthood. However, regimens are limited to first- and second-line in many African settings. Therefore, understanding ...
Consistency of Mycobacterium tuberculosis-specific interferon-gamma responses in HIV-1-infected women during pregnancy and postpartum.
(University of Nairobi., 2012)
Background: We determined the consistency of positive interferon-gamma (IFN-γ) release assays (IGRAs) to detect latent TB infection (LTBI) over one-year postpartum in HIV-1-infected women. Methods: Women with positive IGRAs ...
A Prospective Cohort Study Comparing the Effect of Single-Dose 2 g Metronidazole on Trichomonas vaginalis Infection in HIV-Seropositive Versus HIV-Seronegative Women.
(University of Nairobi, 2013-06)
BACKGROUND:
This analysis compared the frequency of persistent Trichomonas vaginalis (TV) among HIV-seropositive and HIV-seronegative women.
METHODS:
Data were obtained from women enrolled in an open cohort study ...
Latent tuberculosis detection by interferon γ release assay during pregnancy predicts active tuberculosis and mortality in human immunodeficiency virus type 1-infected women and their children.
(University of Nairobi., 2010-12)
BACKGROUND:
We evaluated the prognostic usefulness of interferon γ release assays (IGRAs) for active tuberculosis and mortality in Kenyan human immunodeficiency virus type 1 (HIV-1)-infected women and their infants.
ME ...
Establishing and sustaining a healthy vaginal environment: analysis of data from a randomized trial of periodic presumptive treatment for vaginal infections
(2011)
Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by Gram ...
Home visits during pregnancy enhance male partner HIV counselling and testing in Kenya: a randomized clinical trial.
(University of Nairobi, 2013-08)
BACKGROUND::
HIV testing male partners of pregnant women may decrease HIV transmission to women and promote uptake of prevention of mother-to-child HIV transmission (PMTCT) interventions. However, it has been difficult ...
The Afya Bora Consortium: an Africa-US partnership to train leaders in global health.
(University of Nairobi, 2011)
The Afya Bora Consortium is a partnership of 8 academic health institutions, 4 in Africa and 4 in the United States. The Consortium is developing a Global Health Leadership Fellowship for medical, nursing, and public health ...
Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2.
(Univesity of Nairobi, 2010)
Predicting pregnancy in HIV-1-discordant couples.
(University of Nairobi, 2010-10)
This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy ...