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Use of the Consolidated Framework for Implementation Research (CFIR) to Characterize Healthcare Workers' Perspectives on Financial Incentives to Increase Pediatric HIV Testing.
(University of Nairobi, 2020)
BACKGROUND:
A prior randomized control trial showed financial incentives increase HIV testing rates for children of unknown HIV status. Translating evidence-based interventions such as these to scale requires an ...
Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women.
(University of Nairobi, 2020)
A reservoir of HIV-infected cells that persists despite suppressive antiretroviral therapy (ART) is the source of viral rebound upon ART cessation and the major barrier to a cure. Understanding reservoir seeding dynamics ...
Assessing antigenic drift and phylogeny of influenza A (H1N1) pdm09 virus in Kenya using HA1 sub-unit of the hemagglutinin gene.
(University of Nairobi, 2020)
Influenza A (H1N1) pdm09 virus emerged in North America in 2009 and has been established as a seasonal strain in humans. After an antigenic stasis of about six years, new antigenically distinct variants of the virus emerged ...
Newly diagnosed HIV positive children: a unique index case to improve HIV diagnosis and linkage to care of parents.
(University of Nairobi, 2020)
Newly diagnosed HIV positive children may be unique index cases to identify undiagnosed parents. Data was used from the Pediatric Urgent Start of HAART (NCT02063880) trial, which enrolled hospitalized, ART-naïve, HIV ...
Regular use of depot medroxyprogesterone acetate causes thinning of the superficial lining and apical distribution of HIV target cells in the human ectocervix
(University of Nairobi, 2020)
Background: The hormonal contraceptive depot medroxyprogesterone acetate (DMPA) may be associated with an increased risk of acquiring human immunodeficiency virus (HIV). We hypothesize that DMPA use influences the ectocervical ...
Postpartum metabolic syndrome and high-sensitivity C-reactive protein after gestational hypertension and pre-eclampsia
(University of Nairobi, 2020)
Objective: To evaluate the association between metabolic syndrome (MetS) and high-sensitivity C-reactive protein (hsCRP), a biomarker of chronic inflammation and an independent predictor for cardiovascular disease overall ...
Validating dental age estimation in Kenyan black children and adolescents using the Willems method
(University of Nairobi, 2020)
Purpose: This study aimed to validate the Willems Belgian Caucasian (Willems BC) age estimation model in a Kenyan sample, to develop and validate a Kenyan-specific (Willems KB) age estimation model and to compare the age ...
Conceptual framework for establishing the African Stroke Organization
(University of Nairobi, 2020)
Africa is the world's most genetically diverse, second largest, and second most populous continent, with over one billion people distributed across 54 countries. With a 23% lifetime risk of stroke, Africa has some of the ...
Chewable Antacid Tablets: Are Disintegration Tests Relevant?
(University of Nairobi, 2020)
A recently published FDA guidance on chewable tablets has addressed the quality attributes of this class of dosage forms. This study evaluated disintegration as a quality attribute for a number of commercially available ...
Trends and risk factors associated with stillbirths: A case study of the Navrongo War Memorial Hospital in Northern Ghana.
(University of Nairobi, 2020)
Background
Maternal and Child health remains at the core of global health priorities transcending the Millennium Development Goals into the current era of Sustainable Development Goals. Most low and middle-income countries ...