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Biopsychosocial risk factors and knowledge of cervical cancer among young women: A case study from Kenya to inform HPV prevention in Sub-Saharan Africa
(University of Nairobi, 2020)
Background: Cervical cancer is the second most common female reproductive cancer after breast cancer with 84% of the cases in developing countries. A high uptake of human papilloma virus (HPV) vaccination and screening, ...
The role of alpha-synuclein as ferrireductase in neurodegeneration associated with Parkinson's disease
(University of Nairobi, 2020)
Misfolding of the protein α-synuclein contributes to the formation of the intracellular inclusion, Lewy bodies. Although these structures are not exclusive to Parkinson's disease, nevertheless, their presence in the ...
Modeling the health impact and cost threshold of long-acting ART for adolescents and young adults in Kenya
(University of Nairobi, 2020)
Background: Despite high efficacy of oral antiretroviral therapy (ART), viral suppression among adolescents and young adults (AYA) living with HIV in sub-Saharan Africa (SSA) remains low. Compared to daily oral ART, bimonthly ...
The Canadian retinoblastoma research advisory board: a framework for patient engagement
(University of Nairobi, 2020)
Plain english summary: Retinoblastoma is a rare eye cancer that occurs in one or both eyes of infants and young children as a result of errors in the RB1 gene. There are approximately 2000 retinoblastoma survivors in Canada. ...
Lymphopenia and neutrophilia at admission predicts severity and mortality in patients with COVID-19: a meta-analysis
(University of Nairobi, 2020)
Background: There is a compelling need to identify clinical and laboratory predictors of unfavorable clinical course and death in patients with coronavirus disease (COVID-19). A trend towards low lymphocyte count and high ...
The history of critical care in Kenya
(Elsevier, 2020)
Critical care is a young specialty in Kenya. From its humble beginnings in the 1960s to present day Kenya, the bulk of this service has largely been provided by anaesthetists. We provide a detailed account of the growth ...
Metformin's effectiveness in preventing prednisone-induced hyperglycemia in hematological cancers
(University of Nairobi, 2020)
Background: Research has established the development of steroid-induced hyperglycemia as a glucometabolic side effect of high-dose prednisone therapy. Few studies, however, have demonstrated preventative measures that could ...
Sex determination from dimensions of distal tibiae in adult Kenyans: A discriminant function analysis
(Elsevier, 2020)
Purpose: To assess the utility of the dimensions of the distal tibial articular surface in determining the sex of an individual in a sample Kenyan population. Basic procedures: A total of 156 tibiae were obtained for the ...
Integration of prevention and control measures for female genital schistosomiasis, HIV and cervical cancer
(University of Nairobi, 2020)
Female genital schistosomiasis as a result of chronic infection with Schistosoma haematobium (commonly known as bilharzia) continues to be largely ignored by national and global health policy-makers. International attention ...
Patient- and parent proxy-reported outcome measures for life participation in children with chronic kidney disease: a systematic review
(University of Nairobi, 2020)
Background: The burden of chronic kidney disease (CKD) and its treatment may severely limit the ability of children with CKD to do daily tasks and participate in family, school, sporting and recreational activities. Life ...