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Obstructive Sleep Apnea Awareness among Primary Care Physicians in Africa
(University of Nairobi, 2020)
Rationale: Obstructive sleep apnea (OSA) is a significant health problem among adults and children globally, resulting in decreased quality of life and increased costs of healthcare. For optimal clinical care, primary care ...
Treatment of Patients With Late-Stage Colorectal Cancer: ASCO Resource-Stratified Guideline
(University of Nairobi, 2020)
Purpose: To provide expert guidance to clinicians and policymakers in resource-constrained settings on the management of patients with late-stage colorectal cancer.
Methods: ASCO convened a multidisciplinary, multinational ...
Detection of circulating hepatitis B virus immune escape and polymerase mutants among HBV-positive patients attending Institut Pasteur de Bangui, Central African Republic
(University of Nairobi, 2020)
Background: Previous studies in the Central African Republic (CAR) have reported the presence of hepatitis B virus (HBV) recombinant genotype E/D and a suspicion of immune escape mutants (IEMs), without further investigation ...
Improving the management of hypertension and diabetes: An implementation evaluation of an electronic medical record system in Nairobi County, Kenya
(University of Nairobi, 2020)
Objective: To evaluate the implementation of a novel electronic medical record (EMR) system for management of non-communicable diseases (NCD) (hypertension (HTN) and diabetes mellitus (DM)) in health facilities in informal ...
Seroprevalence of yellow fever, dengue, West Nile and chikungunya viruses in children in Teso South Sub-County, Western Kenya
(University of Nairobi, 2020)
Background: Arboviruses often cause widespread morbidity in children in endemic regions. Data on the burden of arboviruses in Kenyan children are limited.
Objectives: This study was performed to determine the seroprevalence ...
Exogenous lipoid pneumonia in children: A systematic review
(University of Nairobi, 2020)
Objectives: To describe the clinical-radiological-pathological characteristics and treatment outcomes of children with suspected exogenous lipoid pneumonia (ELP).
Design: Systematic review. We searched electronic databases ...
Diversity and function of maternal hiv-1-specific antibodies at the time of vertical transmission
(UoN, 2020)
Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do not become infected. There is evidence that maternal antibodies ...
A review of recent research on Theileria parva: Implications for the infection and treatment vaccination method for control of East Coast fever
(University of Nairobi, 2020)
The infection and treatment (ITM) live vaccination method for control of Theileria parva infection in cattle is increasingly being adopted, particularly in Maasai pastoralist systems. Several studies indicate positive ...
Multidisciplinary approach towards training of the next generation of forensic DNA analysts in Africa; a Kenyan perspective
(University of Nairobi, 2020)
The uptake of forensic DNA testing technologies in Africa has been slow despite the revolutionary technology being discovered and adopted 3 decades ago. African governments and partners have invested in construction and ...
Diversity and Multiplicity of P. falciparum infections among asymptomatic school children in Mbita, Western Kenya
(University of Nairobi, 2020)
Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important surrogate indicators for assessing malaria transmission intensity in different regions of endemicity. Determination of MOI and ...