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Now showing items 1-10 of 12
Establishing and sustaining a healthy vaginal environment:
(2011)
Data from a randomized trial of oral periodic presumptive
treatment (PPT) to reduce vaginal infections were analyzed
to assess the effect of the intervention on a healthy vaginal
environment (normal flora confirmed by ...
Reasons for ineligibility in phase 1 and 2A HIV vaccine clinical trials at Kenya Aids vaccine initiative (KAVI), Kenya
(2011)
With the persistent challenges towards controlling the HIV epidemic, there is an ongoing need for research into HIV vaccines and drugs. Sub-Saharan African countries--worst affected by the HIV pandemic--have participated ...
Loss to Follow-Up as a Competing Risk in an Observational Study of HIV-1 Incidence
(2013)
OBJECTIVE:
Conventional survival estimates may be biased if loss to follow-up (LTF) is associated with the outcome of interest. Our goal was to assess whether the association between sexual risk behavior and HIV-1 ...
Acceptability of medical male circumcision among uncircumcised men in Kenya one year after the launch of the national male circumcision program
(2011)
BACKGROUND:
Numerous studies have demonstrated that male circumcision (MC) reduces the incidence of the Type-1 human immunodeficiency virus (HIV) among heterosexual men by at least half.
METHODS:
One year after the ...
Anal sex, vaginal practices, and HIV incidence in female sex workers in urban Kenya: implications for the development of intravaginal HIV prevention methods.
(Mary Ann Liebert, 2011)
Multiple intravaginal HIV prevention methods, including microbicide gels, barriers, and intravaginal rings, are in clinical development in Africa. Development of intravaginal HIV prevention products requires an understanding ...
Abundant Expression of HIV Target Cells and C-Type Lectin Receptors in the Foreskin Tissue of Young Kenyan Men
(2010)
A biological explanation for the reduction in HIV-1 (HIV) acquisition after male circumcision may be that removal of the foreskin reduces the number of target cells for HIV. The expression of potential HIV target cells and ...
Anal Sex, Vaginal Practices, and HIV Incidence in Female Sex Workers in Urban Kenya: Implications for the Development of Intravaginal HIV Prevention Methods
(2011)
Multiple intravaginal HIV prevention methods, including microbicide gels, barriers, and intravaginal rings, are
in clinical development in Africa. Development of intravaginal HIV prevention products requires an understanding
of ...
Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
(2010)
Persistent genital human immunodeficiency virus type 1
(HIV-1) shedding among women receiving antiretroviral
therapy (ART) may present a transmission risk. We investigated
the associations between genital HIV-1 ...
Implementing voluntary medical male circumcision for HIV prevention in Nyanza Province, Kenya: lessons learned during the first year
(2011)
BACKGROUND:
In 2007, the World Health Organization endorsed male circumcision as an effective HIV prevention strategy. In 2008, the Government of Kenya (GoK) launched the national voluntary medical male circumcision ...
Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.
(University of Nairobi, 2011)
OBJECTIVES:
Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective ...