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Now showing items 31-40 of 83
Treatment Of Cervicitis Is Associated With Decreased Cervical Shedding Of Hiv-1. AIDS
(2001-01-05)
OBJECTIVE: To determine whether cervical mucosal shedding of HIV-1 RNA and HIV-1 infected cells decreases following successful treatment of cervicitis. DESIGN: Prospective interventional study. SETTING: Sexually Transmitted ...
Phylogenetic evaluation of Kenyan HIV type 1 isolates.AIDS Res Hum Retroviruses
(University of Nairobi, 1997-04)
Diversity among global isolates of HIV-1 presents a formidable challenge for vaccine development. As distinct clades of the virus are recognized, it will be important to monitor their geographic distribution and divergence. ...
Efficient isolation of human immunodeficiency virus type 1 RNA from cervical swabs
(University of Nairobi, 1998-08)
An efficient method for the isolation of human immunodeficiency virus type 1 (HIV-1) nucleic acids from dry cervical swabs was developed. HIV-1 gag and env were detected in 96% (25 of 26) and 81% (21 of 26), respectively, ...
The Effect Of Hormonal Contraception On Genital Tract Shedding Of Hiv-1.aids
(University of Nairobi, 2004-01-23)
OBJECTIVE: A previous cross-sectional study reported that hormonal contraception may be associated with increased infectivity in HIV-1 infected women. We conducted a prospective study to determine if cervical shedding of ...
Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA shedding, and breast infections
(2001)
To determine the effects of plasma, genital, and breast milk human immunodeficiency virus type 1 (HIV-1) and breast infections on perinatal HIV-1 transmission, a nested case-control study was conducted within a randomized ...
Oligonucleotide ligation assay detects HIV drug resistance associated with virologic failure among antiretroviral-naive adults in Kenya
(University of Nairobi, 2014-11)
BACKGROUND:
Transmitted drug resistance (TDR) is increasing in some areas of Africa. Detection of TDR may predict virologic failure of first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral ...
A Prospective Study Of Risk Factors For Herpes Simplex Virus Type 2 Acquisition Among High-risk Hiv-1 Seronegative Women In Kenya
(University of Nairobi, 2009)
Objectives: Several studies have demonstrated an association between herpes simplex virus type 2 (HSV-2) and HIV-1, but available data on risk factors for HSV-2 acquisition are limited. The objective of this analysis was ...
Infants with late breast milk acquisition of HIV-1 generate interferon-gamma responses more rapidly than infants with early peripartum acquisition
(2009)
Infants infected with HIV-1 after the first month of life have a lower viral
set-point and slower disease progression than infants infected before 1
month. We investigated the kinetics of HIV-1-specific CD8+ T ...
Longitudinal analysis of human immunodeficiency virus type 1 RNA in breast milk and of its relationship to infant infection and maternal disease
(2003-03)
Transmission of human immunodeficiency virus type 1 (HIV-1) via breast-feeding can occur throughout lactation. Defining both fluctuation in breast-milk virus level over time and how breast-milk virus correlates with ...
Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children
(2007)
OBJECTIVES:
To describe the early response to World Health Organization (WHO)-recommended nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line highly active antiretroviral therapy (HAART) in HIV-1-infected ...