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Postpartum metabolic syndrome and high-sensitivity C-reactive protein after gestational hypertension and pre-eclampsia
(University of Nairobi, 2020)
Objective: To evaluate the association between metabolic syndrome (MetS) and high-sensitivity C-reactive protein (hsCRP), a biomarker of chronic inflammation and an independent predictor for cardiovascular disease overall ...
Validating dental age estimation in Kenyan black children and adolescents using the Willems method
(University of Nairobi, 2020)
Purpose: This study aimed to validate the Willems Belgian Caucasian (Willems BC) age estimation model in a Kenyan sample, to develop and validate a Kenyan-specific (Willems KB) age estimation model and to compare the age ...
Psychotic-like experiences among 9,564 Kenyan adolescents and young adults.
(Elsevier B.V., 2021)
Objective: To investigate the prevalence and characteristics of psychotic-like experiences (PLE) in a large cohort of Kenyan adolescents and young adults.
Method: The Washington Early Recognition Center Affectivity and ...
Urine Biomarker Assessment of Infant Adherence to Isoniazid Prophylaxis
(University of Nairobi, 2021)
We assessed adherence in an infant tuberculosis prevention trial in Kenya with a urine isoniazid metabolite-detecting dipstick. Ninety-seven infants had 155 assays performed; 77 (49.7%) were found to be positive despite ...
Prevalence and correlates of common mental health problems and recent suicidal behaviour among female sex workers in Nairobi, Kenya: findings from the Maisha Fiti study
(University of Nairobi, 2021)
Adverse childhood experiences (ACEs), poverty, violence and harmful alcohol/substance are associated with poor mental health outcomes in the general population. These risks are likely to be exacerbated among Female Sex ...
Testing the EPDS and PHQ-9 Among Peripartum Adolescents in Nairobi, Kenya: a Mixed-Methods Study
(University of Nairobi, 2021)
Background:
Cognitive interviewing is a well-recognised methodology to identify clinical and commonsensical relevance of mental health questionnaire items by our research participants. Depression is amongst the most common ...
Conceptual framework for establishing the African Stroke Organization
(University of Nairobi, 2020)
Africa is the world's most genetically diverse, second largest, and second most populous continent, with over one billion people distributed across 54 countries. With a 23% lifetime risk of stroke, Africa has some of the ...
Feasibility of Family-Assisted Severity of Illness Monitoring for Hospitalized Children in Low-Income Settings
(University of Nairobi, 2021-02)
Objectives: To determine the feasibility of having caregivers assist in recognition of clinical deterioration in children hospitalized with febrile illness in a resource-limited setting.
Design: Single-center, prospective, ...
Femtosecond laser-assisted big bubble for deep anterior lamellar keratoplasty
(University of Nairobi, 2021-01)
Purpose: To assess the utility of a femtosecond laser-assisted stromal channel to assist the creation of a big bubble (BB) for deep anterior lamellar keratoplasty (DALK) surgery in cadaveric corneas.
Setting: L V Prasad ...
Chewable Antacid Tablets: Are Disintegration Tests Relevant?
(University of Nairobi, 2020)
A recently published FDA guidance on chewable tablets has addressed the quality attributes of this class of dosage forms. This study evaluated disintegration as a quality attribute for a number of commercially available ...