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HIV-1 disease progression in breast-feeding and formula-feeding mothers:
(2007)
Background. There is conflicting evidence regarding the effects of breast‐feeding on maternal mortality from human immunodeficiency virus type 1 (HIV‐1) infection, and little is known about the effects of breast‐feeding ...
Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children
(2007)
OBJECTIVES:
To describe the early response to World Health Organization (WHO)-recommended nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line highly active antiretroviral therapy (HAART) in HIV-1-infected ...
Human leukocyte antigen (HLA) B*18 and protection against mother-to-child HIV type 1 transmission.
(2004)
Human leukocyte antigen (HLA) molecules regulate the cellular immune system and may be determinants of infant susceptibility to human immunodeficiency virus type 1 (HIV-1) infection. Molecular HLA typing for class I alleles ...
Early response to highly active antiretroviral therapy in HIV-1-infected Kenyan children.
(2007)
To describe the early response to World Health Organization (WHO)-recommended nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line highly active antiretroviral therapy (HAART) in HIV-1-infected Kenyan ...
HV-1-specific cytotoxic T lymphocytes and breast milk HIV-1 transmission.
(2009)
Breast-feeding by infants exposed to human immunodeficiency virus type 1 (HIV-1) provides an opportunity to assess the role played by repeated HIV-1 exposure in eliciting HIV-1-specific immunity and in defining whether ...
Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants.
(2005)
Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in viral control has not been ...
Comparison of techniques for HIV-1 RNA detection and quantitation in cervicovaginal secretions.
(University of Nairobi., 2001-02)
PRINCIPLES:
HIV-1 in female genital secretions has been measured using swabs, Sno Strips (Akorn, Inc., Buffalo Grove, IL), and cervicovaginal lavage (CVL), but little is known regarding the comparability of these collection ...
Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants[star]
(2005)
Recombinant modified vaccinia virus Ankara expressing HIV-1 antigens (MVA.HIVA) was used in ELISpot assays to monitor HIV-1-specific T cell responses in infants. Responses to MVA.HIVA and HIV-1 peptides were examined in ...
Morbidity among HIV-1–infected mothers in Kenya prevalence and correlates of illness during 2-year postpartum follow-up
(2007)
Background: Much of the burden of morbidity affecting women of
childbearing age in sub-Saharan Africa occurs in the context of HIV-1
infection. Understanding patterns of illness and determinants of
disease in HIV-1–infected ...
Low risk of death, but substantial program attrition, in pediatric HIV treatment cohorts in Sub-Saharan Africa
(University of Nairobi., 2008-12)
BACKGROUND:
To date, an estimated 10% of children eligible for antiretroviral treatment (ART) receive it, and the frequency of retention in programs is unknown. We evaluated the 2-year risks of death and loss to follow-up ...