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A randomized, double-blind, placebo-controlled study of buprenorphine was carried out in 20 patients after cholecystectomy. The drug was given on "patient demand" either i.m. (0.15 mg) or sublingually (0.2 mg) with a minimum dose interval of 30 min. Over the 24-h study period the mean demand by the sublingual route was 0.8 mg (range 0.6-1.2 mg) and by the i.m. route 0.66 mg (range 0.45-0.9 mg). Pain relief, by visual analogue scales and grading, was similar. Plasma buprenorphine concentrations varied more after sublingual administration. Either route was effective for the treatment of pain when administered by "patient demand".
(1986)
A randomized, double-blind, placebo-controlled study of buprenorphine was carried out in 20 patients after cholecystectomy. The drug was given on "patient demand" either i.m. (0.15 mg) or sublingually (0.2 mg) with a minimum ...
Ophthalmia neonatorum in Nairobi, Kenya: the roles of Neisseria gonorrhoeae and Chlamydia trachomatis
(University of Nairobi,, 1986-05)
Among 149 consecutive infants with ophthalmia neonatorum in Nairobi, Neisseria gonorrhoeae was recovered from 43%, Chlamydia trachomatis from 13%, and both microorganisms from 4%. Three of five isolates of C. trachomatis ...
Comparison between pressures measured from the proximal external jugular vein and a central vein.
(1986)
Mean venous pressures were measured in 20 patients in whom a catheter, inserted via the external jugular vein, failed to pass centrally. The catheter used had a rounded end and two side holes. Pressures were measured with ...
Heterochromatin Staining Pattern Of Quail-chicken Hybrid Lymphocytes.
(University Of Nairobi, 1986)
Feulgen-Rossenbeck staining of lymphoid cells of quail-chicken hybrids in histologic sections revealed a pattern of heterochromatin arrangement distinguishable from that of either parental type. During interphase, hybrid ...
Puncture of unilateral renal cyst in utero.
(1986)
Although most authors do not recommend prenatal puncture of a unilateral single cystic renal mass, in case the contralateral kidney is normal and there is sufficient amniotic fluid, this case report shows that the procedure, ...
Altered Expression Of Epidermal Growth Factor Receptors In Human Bladder And Lung Tumours
(University Of Nairobi, 1986)
The expression of epidermal growth factor (EGF) receptors on 31 primary bladder and 109 lung tumours was evaluated by immunohistology using two monoclonal antibodies which recognise either the external ligand binding domain ...
Sero-epidemiology of Toxoplasma gondii infection in young children in Nairobi, Kenya
(University of Nairobi, 1986)
The exposure of 127 pre-school and young schoolchildren to Toxoplasma gondii was investigated by a serological survey of its antibody by means of the passive haemagglutination technique. The significant rise of prevalence ...
Immunoglobin M and malarial antibody levels in hyper-reactive malarial splenomegaly
(1986)
In a study of chronic splenomegaly in Kenya, hyper-reactive malarial splenomegaly, our preferred name for tropical splenomegaly syndrome, was diagnosed in 38 patients. This diagnosis was based on exclusion of other conditions ...
Essential oil of Plectranthus marrubioides Benth
(1986)
The average essential oil contents of Plectranthus marrubioides leave was determined to be 4.1 %, calculated on a moisture-free basis. The gas liquid chromatography (GLC) analysis of the oil showed that the average camphor ...