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Rapid Decline in Risk of HIV-l Acquisition After Enrollment in a Vaccine Preparedness Cohort of Kenyan Prostitutes: Implications for the Design of HIV -1 Vaccine Efficacy Trials
(2002-02)
Background: In designing HIY-l vaccine efficacy trials, it will be important to accounrfor changes in HIY -1 incidence, especially changes over time and while participating in riskreduction programs.
Methods: Data from ...
Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial
(2004)
To test the hypothesis that micronutrient supplementation decreases genital HIV-1 shedding, a double-blind, randomized, placebo-controlled trial of 6 weeks of multivitamin plus selenium supplementation vs. placebo was ...
Vaginal washing and increased risk of HIV-1 acquisition among African women: a 10-year prospective study
(2006)
BACKGROUND:
No prospective study has examined the risk of HIV-1 acquisition associated with vaginal washing, although intravaginal practices have been identified as potentially important contributors to HIV-1 ...
Virus load during primary Human Immunodeficiency Virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women.
(2002)
We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes ...
Hormonal contraception and risk of sexually transmitted disease acquisition: results from a prospective study
(2001)
OBJECTIVES:
To examine the relationship between use of oral contraceptive pills or depot medroxyprogesterone acetate and sexually transmitted disease acquisition.
STUDY DESIGN:
Prospective cohort included 948 ...
Primary human immunodeficiency virus type 1 infection: clinical manifestations among women in Mombasa, Kenya
(2000)
The occurrence of clinical manifestations associated with primary human immunodeficiency virus type 1 (HIV-1) infection was evaluated in a prospective cohort study of female sex workers in Mombasa, Kenya. Among 103 women ...
High levels of cervical HIV-1 RNA during early HIV-1 infection.
(2006)
Few data are available on genital tract viral replication early after HIV-1 acquisition, when infectivity is high. We compared cervical HIV-1 RNA from 60 women with paired samples from within 90 days after HIV-1 acquisition ...
Shedding Of Human Herpesvirus 8 In Oral And Genital Secretions From Hiv-1-seropositive And -seronegative Kenyan Wo
(University of Nairobi, 2004-08-01)
Polymerase chain reaction was used to determine the prevalence and correlates of human herpesvirus 8 (HHV8) in saliva, mouth, cervical, vaginal, plasma, and peripheral-blood mononuclear cell (PBMC) samples from 174 ...
A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression.
(2007)
We investigated the association between albumin levels and HIV-1 disease progression among 78 Kenyan women followed from before infection through a median of 70 months. With HIV-1 acquisition, median albumin decreased from ...
Hormonal Contraception And Risk Of Cervical Infections Among Hiv-1-seropositive Kenyan Women
(University of Nairobi, 2004-11-05)