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Maternal Human Leukocyte Antigen - A*2301 Is Associated with Increased Mother-to-Child HIV-1 Transmission
(2010)
We examined associations between maternal HLA and vertical HIV-1 transmission in a perinatal cohort of 277 HIV-infected women in Nairobi. HLA class I genes were amplified using sequence-specific oligonucleotide probes and ...
Cofactors for HIV-1 incidence during pregnancy and postpartum period.
(2010-10)
OBJECTIVES:
to estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.
DESIGN:
retrospective study among women who were HIV seronegative during pregnancy.
METHODS:
mothers ...
Latent TB detection by interferon gamma release assay (IGRA) in pregnancy predicts active TB and mortality in HIV-1 infected women and their children
(2010)
Background—We evaluated the prognostic utility of interferon-gamma release assays (IGRAs)
for active tuberculosis (TB) and mortality in Kenyan HIV-1 infected women and their infants.
Methods—Prevalence and correlates of ...
Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition
(University of Nairobi., 2010-06)
The C868T single nucleotide polymorphism (SNP) in the CD4 receptor encodes an amino acid change that could alter its structure and influence human immunodeficiency virus (HIV-1) infection risk. HIV-1-infected pregnant women ...
Illness during pregnancy and bacterial vaginosis are associated with in-utero HIV-1 transmission
(University of Nairobi., 2010-01)
HIV-1 transmission in utero accounts for 20-30% of vertical transmission events in breast-feeding populations. In a prospective study of 463 HIV-1-infected mothers and infants, illness during pregnancy was associated with ...
Predictors of mortality in HIV-1 infected children on antiretroviral therapy in Kenya:
(2010)
Background: Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It is
important to define correlates of mortality in order to improve outcome.
Methods: HIV-1-infected ...
Cofactors for HIV-1 Incidence during Pregnancy and Postpartum Period
(2010)
Objectives
To estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.
Design
Retrospective study among women who were HIV seronegative during pregnancy.
Methods
Mothers ...