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Now showing items 1-9 of 9
The importance of core groups in the epidemiology and control of HIV-1 infection
(1991)
In Africa, HIV transmission occurs mainly through heterosexual intercourse. High-frequency transmitter core groups are key to the epidemiology of HIV-1 and STD on the continent. The rapid growth of the HIV-1 epidemic in ...
Isoniazid preventive therapy for tuberculosis in HIV-1-infected adults: results of a randomized controlled trial
(1997)
OBJECTIVES:
To determine the efficacy of isoniazid 300 mg daily for 6 months in the prevention of tuberculosis in HIV-1-infected adults and to determine whether tuberculosis preventive therapy prolongs survival in ...
Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection
(1995)
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several ...
Human immunodeficiency virus infection among high-risk seronegative prostitutes in Nairobi
(1993)
To determine the frequency and duration of antibody-negative human immunodeficiency virus (HIV) infection among heterosexually exposed African women, 56 HIV-seronegative female prostitutes in Nairobi were studied. Polymerase ...
Resistance to HIV-1 infection among African sex workers is associated with global hyporesponsiveness in interleukin 4 production.
(2001)
We previously identified HIV-1 resistant prostitutes who remain persistently HIV-1 PCR- and
antibody-negative despite continued heavy exposure to HIV-1 through sex work. We hypothesized
that differences in virus-specific ...
Stable antenatal HIV-1 seroprevalence with high population mobility and marked seroprevalence variation among sentinel sites within Nairobi, Kenya.
(1999)
Objectives: To monitor and analyse trends in HIV-1 seroprevalence among
antenatal women in Nairobi, Kenya.
Design: Six sequential surveys were carried out among antenatal clinic attenders at
four Nairobi City Council ...
A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings
(2000)
Our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (STIs) and HIV-1 in a cohort of Nairobi female sex workers (FSWs). A questionnaire was ...
Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts
(2000)
In Kenya, the median incubation time to AIDS in seroconverting sex workers is 4 years;
this incubation time is specific to female sex workers.We studied the influence of acute sexually transmitted infections (STIs) on ...
Risk factors for genital ulcerations in Kenyan sex workers. The role of human immunodeficiency virus type 1 infection.
(1997)
BACKGROUND AND OBJECTIVES: Genital ulcer disease (GUD) is a major risk factor for human immunodeficiency virus (HIV) transmission. Cross-sectional studies have suggested that HIV infection may itself predispose to genital ...